Evidence map›Paper›PMID 19389264›Full record

ArticleGenetics, selection, evolution : GSE2009

Mapping quantitative trait loci (QTL) in sheep. I. A new male framework linkage map and QTL for growth rate and body weight.

Herman W Raadsma, Peter C Thomson, Kyall R Zenger, Colin Cavanagh, Mary K Lam, Elisabeth Jonas, Marilyn Jones, Gina Attard, David Palmer, Frank W Nicholas

Abstract readEvaluation Study
In one paragraph

Article in Genetics, selection, evolution : GSE, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Herman W RaadsmaReproGen--Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, University of Sydney, 425 Werombi Road, Camden, NSW 2570, Australia. raadsma@camden.usyd.edu.au
Peter C Thomson
Kyall R Zenger
Colin Cavanagh
Mary K Lam
Elisabeth Jonas
Marilyn Jones
Gina Attard
David Palmer
Frank W Nicholas

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A male sheep linkage map comprising 191 microsatellites was generated from a single family of 510 Awassi-Merino backcross progeny. Except for ovine chromosomes 1, 2, 10 and 17, all other chromosomes yielded a LOD score difference greater than 3.0 between the best and second-best map order. The map is on average 11% longer than the Sheep Linkage Map v4.7 male-specific map. This map was employed in quantitative trait loci (QTL) analyses on body-weight and growth-rate traits between birth and 98 weeks of age. A custom maximum likelihood program was developed to map QTL in half-sib families for non-inbred strains (QTL-MLE) and is freely available on request. The new analysis package offers the advantage of enabling QTL x fixed effect interactions to be included in the model. Fifty-four putative QTL were identified on nine chromosomes. Significant QTL with sex-specific effects (i.e. QTL x sex interaction) in the range of 0.4 to 0.7 SD were found on ovine chromosomes 1, 3, 6, 11, 21, 23, 24 and 26.

Indexed as

Body WeightQuantitative Trait LociAnimalsChromosome MappingChromosomes, MammalianFemaleInbreedingMaleMicrosatellite RepeatsModels, GeneticSheep, DomesticSpecies Specificity

Identifiers

PMID19389264
PMCPMC2686678

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.