Evidence map›Paper›PMID 19389002›Full record

Trial reportBJU international2009

The number of procedures required to achieve optimal competency with male circumcision: findings from a randomized trial in Rakai, Uganda.

Valerian Kiggundu, Stephen Watya, Godfrey Kigozi, David Serwadda, Fred Nalugoda, Denis Buwembo, Absolom Settuba, Margaret Anyokorit, James Nkale, Nehemiah Kighoma and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BJU international, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  8. Article
  9. Canadian Urological Association guideline on the care of the normal foreskin and neonatal circumcision in Canadian infants (full version).Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Article
  10. Trends in the Marginal Cost of Male Circumcision in Rural Rakai Uganda.Journal of acquired immune deficiency syndromes (1999) · 2016
    Article
  11. Surgical Outcomes of Newly Trained ShangRing Circumcision Providers.Journal of acquired immune deficiency syndromes (1999) · 2016
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Implementation science for the prevention and treatment of HIV/AIDS.Journal of acquired immune deficiency syndromes (1999) · 2010
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Valerian KiggunduRakai Health Sciences Program, Entebbe, Uganda.
Stephen Watya
Godfrey Kigozi
David Serwadda
Fred Nalugoda
Denis Buwembo
Absolom Settuba
Margaret Anyokorit
James Nkale
Nehemiah Kighoma
Victor Ssempijja
Maria Wawer
Ronald H Gray

Funding

Male Circumcision Trial for HIV Prevention, Rakai-UgandaU01AI051171 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2002 to 2006
$8.9M
International Training/Research in Population and Health, UgandaD43TW001508 · FIC · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2000 to 2010
$2.1M
SPECIAL POSTDOCTORAL RESEARCH PROGRAM IN AIDST22TW000015 · FIC · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SCOTT, GWENDOLYN B. · 1988 to 1999
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FIC NIH HHS 5D43TW001508FIC NIH HHS D43TW00015FIC NIH HHS D43 TW001508FIC NIH HHS T22 TW000015NIAID NIH HHS U01 AI051171NIAID NIH HHS U1AI51171
6 · The paper itself

Abstract

objectiveTo assess the number of procedures required to achieve optimal competency (time required for surgery with minimal adverse events) in Rakai, Uganda, and thus facilitate the development of guidelines for training providers, as male circumcision reduces the acquisition of human immunodeficiency virus (HIV) in men and is recommended for HIV prevention. PATIENTS AND

methodsIn a randomized trial, 3011 men were circumcised, using the sleeve method, by six physicians who had completed training, which included 15-20 supervised procedures. The duration of surgery from local anaesthesia to wound closure, moderate or severe surgery-related adverse events (AEs), and wound healing were assessed in relation to the number of procedures done by each physician.

resultsThe median age of the patients was 24 years. The number of procedures per surgeon was 20-981. The mean time required to complete surgery was approximately 40 min for the first 100 procedures and declined to 25 min for the subsequent 100 circumcisions. After controlling for the number of procedures there was no significant difference in duration of the surgery by patient HIV status or age. The rate of moderate and severe AEs was 8.8% (10/114) for the first 19 unsupervised procedures after training, 4.0% for the next 20-99 (13/328) and 2.0% for the last 100 (P for trend, 0.003). All AEs resolved with management.

conclusionThe completion of more than 100 circumcisions was required before newly trained physicians achieved the optimum duration of surgery. AEs were higher immediately after training and additional supervision is needed for at least the first 20 procedures after completing training.

Indexed as

AdolescentAdultCircumcision, MaleClinical CompetenceHIV SeronegativityHIV SeropositivityHumansMaleMiddle AgedPostoperative ComplicationsTime FactorsTreatment OutcomeUgandaYoung Adult

Identifiers

PMID19389002
PMCPMC2748867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.