ArticleEuropean radiology2009
Coronary calcium score as gatekeeper for 64-slice computed tomography coronary angiography in patients with chest pain: per-segment and per-patient analysis.
Article in European radiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic performance of coronary CT angiography for stenosis detection according to calcium score: systematic review and meta-analysis.European radiology · 2012Pooled it
- Influence of coronary calcification on the diagnostic accuracy of 64-slice computed tomography coronary angiography: a systematic review and meta-analysis.The international journal of cardiovascular imaging · 2012Pooled it
- The Diagnostic Performance of Coronary CT Angiography for the Assessment of Coronary Stenosis in Calcified Plaque.PloS one · 2016Trial
- Coronary Calcium Scoring as Prediction of Coronary Artery Diseases with Low-Dose Dual-Source CT.Journal of cardiovascular development and disease · 2025Article
- Preoperative assessment of coronary stenosis through ordinary chest CT for patients scheduled total hip or knee arthroplasty.Frontiers in cardiovascular medicine · 2025Article
- [Assessment of Coronary Stenosis Using Coronary CT Angiography in Patients with High Calcium Scores: Current Limitations and Future Perspectives].Journal of the Korean Society of Radiology · 2024Review
- The Value of Coronary Computed Tomography Angiography in Patients with a High Calcium Score.The journal of Tehran Heart Center · 2023Article
- The novel HFrontiers in cardiovascular medicine · 2023Article
- Article
- Computed tomography independent quantitative determinants of CAD-RADS 4 versus CAD-RADS 3 for calcified coronary lesions.Polish journal of radiology · 2022Article
- Reduced Axial Scan Length Coronary Calcium Scoring Reduces Radiation Dose and Provides Adequate Clinical Decision-Making Before Coronary CT Angiography.Tomography (Ann Arbor, Mich.) · 2020Article
- Calcium scoring: a personalized probability assessment predicts the need for additional or alternative testing to coronary CT angiography.European radiology · 2020Article
- Natural course of coronary artery calcium progression in Asian population with an initial score of zero.BMC cardiovascular disorders · 2020Article
- Modified Subtraction Coronary CT Angiography with a Two-Breathhold Technique: Image Quality and Diagnostic Accuracy in Patients with Coronary Calcifications.Korean journal of radiology · 2019Article
- Synchrotron radiation computed tomography assessment of calcified plaques and coronary stenosis with different slice thicknesses and beam energies on 3D printed coronary models.Quantitative imaging in medicine and surgery · 2019Article
- An investigation of correlation between left coronary bifurcation angle and hemodynamic changes in coronary stenosis by coronary computed tomography angiography-derived computational fluid dynamics.Quantitative imaging in medicine and surgery · 2017Article
- Subtraction coronary computed tomography in patients with severe calcification.The international journal of cardiovascular imaging · 2015Article
- The challenge of coronary calcium on coronary computed tomographic angiography (CCTA) scans: effect on interpretation and possible solutions.The international journal of cardiovascular imaging · 2015Review
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We sought to investigate the performance of 64-slice CT in symptomatic patients with different coronary calcium scores. Two hundred patients undergoing 64-slice CT coronary angiography for suspected coronary artery disease were enrolled into five groups based on Agatston calcium score using the Mayo Clinic risk stratification: group 1: score 0, group 2: score 1-10, group 3: score 11-100, group 4: score 101-400, and group 5: score > 401. Diagnostic accuracy for the detection of significant (>/=50% lumen reduction) coronary artery stenosis was assessed on a per-segment and per-patient base using quantitative coronary angiography as the gold standard. For groups 1 through 5, sensitivity was 97, 96, 91, 90, 92%, and specificity was 99, 98, 96, 88, 90%, respectively, on a per-segment basis. On a per-patient basis, the best diagnostic performance was obtained in group 1 (sensitivity 100% and specificity 100%) and group 5 (sensitivity 95% and specificity 100%). Progressively higher coronary calcium levels affect diagnostic accuracy of CT coronary angiography, decreasing sensitivity and specificity on a per-segment base. On a per-patient base, the best results in terms of diagnostic accuracy were obtained in the populations with very low and very high cardiovascular risk.
Indexed as
Identifiers
19387651What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.