Evidence map›Paper›PMID 19387465›Full record

ArticleLeukemia2009

A novel pedigree with heterozygous germline RUNX1 mutation causing familial MDS-related AML: can these families serve as a multistep model for leukemic transformation?

T Ripperger, D Steinemann, G Göhring, J Finke, C M Niemeyer, B Strahm, B Schlegelberger

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Review
  3. Beyond PathogenicCancers · 2022
    Review
  4. Review
  5. Review
  6. Zebrafish Cancer Predisposition Models.Frontiers in cell and developmental biology · 2021
    Review
  7. Article
  8. The clinical heterogeneity ofResearch and practice in thrombosis and haemostasis · 2020
    Article
  9. Monitoring and treatment of MDS in genetically susceptible persons.Hematology. American Society of Hematology. Education Program · 2019
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Myeloid neoplasms with germline DDX41 mutation.International journal of hematology · 2017
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. A role for RUNX1 in hematopoiesis and myeloid leukemia.International journal of hematology · 2013
    Review
  20. Familial aggregation of acute myeloid leukemia and myelodysplastic syndromes.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

T Ripperger
D Steinemann
G Göhring
J Finke
C M Niemeyer
B Strahm
B Schlegelberger
Medizinische Hochschule Hannover · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Germ-Line MutationHeterozygoteModels, BiologicalAdolescentCore Binding Factor Alpha 2 SubunitFemaleHumansKaryotypingLeukemia, Myeloid, AcuteMaleMyelodysplastic SyndromesPedigreeCore Binding Factor Alpha 2 Subunit

Identifiers

PMID19387465
OpenAlexW1982323278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.