Evidence map›Paper›PMID 19386512›Full record

ReviewSeminars in immunology2009

Barrier immunity and IL-17.

Benjamin R Marks, Joe Craft

Abstract readReview
In one paragraph

Review in Seminars in immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. The Deletion of IL-17A EnhancesJournal of inflammation research · 2022
    Article
  5. Article
  6. Immune Response to MucosalFrontiers in immunology · 2019
    Review
  7. Review
  8. Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats.Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
  9. Frontiers in cellular and infection microbiology · 2018
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Benjamin R MarksDepartment of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Joe Craft

Funding

IMMUNE RESPONSES IN LUPUSR37AR040072 · NIAMS · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR · 2000 to 2025
$7.4M
Yale Rheumatic Diseases Research Core CenterP30AR053495 · NIAMS · YALE UNIVERSITY · PI SHLOMCHIK, WARREN D · 2007 to 2017
$7.0M
GENETIC ANALYSIS OF T CELLS IN LUPUSR01AR044076 · NIAMS · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR · 1996 to 2010
$4.1M
MOLECULAR CHARACTERIZATION OF THE SNRNP POLYPEPTIDESR01AR040072 · NIAMS · YALE UNIVERSITY · PI Joseph Edgar Craft · 1990 to 2026
$2.5M
NIAMS NIH HHS AR40072NIAMS NIH HHS AR44076NIAMS NIH HHS P30 AR053495NIAMS NIH HHS R01 AR040072NIAMS NIH HHS R01 AR044076NIAMS NIH HHS R37 AR040072
6 · The paper itself

Abstract

CD4+ T(H)17 cells display a featured role in barrier immunity. This effector population of T cells is important for clearance of microorganisms but can also promote autoimmunity at barrier sites. Recent work has indicated that these effector cells share a pathway with CD4+ regulatory T cells (T(R) cells) that also have a critical function in barrier protection and immune regulation. The development and function of T(H)17 cells, and their relationship with T(R) cells are discussed.

Indexed as

AnimalsAutoimmune DiseasesCD4-Positive T-LymphocytesCell DifferentiationGastrointestinal TractHumansImmunity, CellularImmunity, MucosalInfectionsInterleukin-17LungSignal TransductionSkinT-Lymphocytes, RegulatoryTranscriptional ActivationInterleukin-17

Identifiers

PMID19386512
PMCPMC2692766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.