ArticleCell communication and signaling : CCS2009
Regulation of cellular proliferation, differentiation and cell death by activated Raf.
Article in Cell communication and signaling : CCS, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- From Waste to Functional Feed Ingredient: Biochemical and SHK-1 Cell Line Evaluation of Black Soldier Fly Larvae for Aquaculture Nutrition.Antioxidants (Basel, Switzerland) · 2025Article
- Article
- An immediate-late gene expression module decodes ERK signal duration.Molecular systems biology · 2017Article
- Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development.The Journal of biological chemistry · 2017Article
- Relative influence of c-Kit expression and epidermal growth factor receptor gene amplification on survival in patients with non-small cell lung cancer.Oncology letters · 2014Article
- Ephrin-B2 controls PDGFRβ internalization and signaling.Genes & development · 2013Article
- Abolished adherence alters signaling pathways in phorbol ester-induced human U937 cells.Cell communication and signaling : CCS · 2011Article
- A novel MCF-10A line allowing conditional oncogene expression in 3D culture.Cell communication and signaling : CCS · 2011Article
- Phosphatidylserine-dependent neuroprotective signaling promoted by docosahexaenoic acid.Prostaglandins, leukotrienes, and essential fatty acidsArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The protein kinases Raf-1, A-Raf and B-Raf connect receptor stimulation with intracellular signaling pathways and function as a central intermediate in many signaling pathways. Gain-of-function experiments shed light on the pleiotropic biological activities of these enzymes. Expression experiments involving constitutively active Raf revealed the essential functions of Raf in controlling proliferation, differentiation and cell death in a cell-type specific manner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.