Evidence map›Paper›PMID 19383089›Full record

ReviewJournal of neurochemistry2009

Olfactory receptors: G protein-coupled receptors and beyond.

Marc Spehr, Steven D Munger

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of neurochemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 206 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The bacteria of a fig community.Microbiology spectrum · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Identifying Key Regulators in Odorant Receptor Trafficking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Article
  14. The anticonvulsant and mood-stabilizing drug valproic acid attractsbioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Marc SpehrDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, Germany.
Steven D Munger
RWTH Aachen University · DEUniversity of Maryland, Baltimore · US

Funding

Transduction mechanisms and CNS targets of GC-D neuronsR01DC005633 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE · PI MUNGER, STEVEN D · 2003 to 2014
$3.5M
Chemosensory receptors and the basis of specificityR01DC005786 · NIDCD · UNIVERSITY OF MARYLAND BALTIMORE · PI MUNGER, STEVEN D · 2002 to 2009
$2.5M
NIDCD NIH HHS DC005633NIDCD NIH HHS DC005786NIDCD NIH HHS R01 DC005633NIDCD NIH HHS R01 DC005786
6 · The paper itself

Abstract

Sensing the chemical environment is critical for all organisms. Diverse animals from insects to mammals utilize highly organized olfactory system to detect, encode, and process chemostimuli that may carry important information critical for health, survival, social interactions and reproduction. Therefore, for animals to properly interpret and react to their environment it is imperative that the olfactory system recognizes chemical stimuli with appropriate selectivity and sensitivity. Because olfactory receptor proteins play such an essential role in the specific recognition of diverse stimuli, understanding how they interact with and transduce their cognate ligands is a high priority. In the nearly two decades since the discovery that the mammalian odorant receptor gene family constitutes the largest group of G protein-coupled receptor (GPCR) genes, much attention has been focused on the roles of GPCRs in vertebrate and invertebrate olfaction. However, is has become clear that the 'family' of olfactory receptors is highly diverse, with roles for enzymes and ligand-gated ion channels as well as GPCRs in the primary detection of olfactory stimuli.

Indexed as

AnimalsHumansOdorantsOlfactory PerceptionReceptors, G-Protein-CoupledSmellReceptors, G-Protein-Coupled

Identifiers

PMID19383089
PMCPMC4455932
OpenAlexW2028470971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.