ArticleMedical oncology (Northwood, London, England)2010
Platelet count: association with prognosis in lung cancer.
Article in Medical oncology (Northwood, London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Prognostic value of pretreatment platelet counts in lung cancer: a systematic review and meta-analysis.BMC pulmonary medicine · 2020Pooled it
- Prognostic value of pretreatment serum fibrinogen in young patients with small cell lung cancer: A cross-sectional study.Health science reports · 2023Article
- Pro-Tumorigenic and Thrombotic Activities of Platelets in Lung Cancer.International journal of molecular sciences · 2023Review
- Comparing prognostic value of preoperative platelet indexes in patients with resectable gastric cancer.Scientific reports · 2022Article
- Analysis of risk factors and gene mutation characteristics of different metastatic sites of lung cancer.Cancer medicine · 2022Article
- Pretreatment plasma fibrinogen and serum albumin levels predict therapeutic efficacy of concurrent radiochemotherapy for esophageal squamous cell cancer.Frontiers in oncology · 2022Article
- What's the difference between lung adenocarcinoma and lung squamous cell carcinoma? Evidence from a retrospective analysis in a cohort of Chinese patients.Frontiers in endocrinology · 2022Article
- The association between thrombocytosis and subtype of lung cancer: a systematic review and meta-analysis.Translational cancer research · 2021Article
- Platelet/lymphocyte ratio is a significant prognostic factor for targeted therapy in patients with EGFR-mutated non-small-cell lung cancer.The Journal of international medical research · 2020Article
- PLR and NLR Are Poor Predictors of Survival Outcomes in Sarcomas: A New Perspective From the USSC.The Journal of surgical research · 2020Article
- The Position of Neutrophils-To-Lymphocytes and Lymphocytes-To-Platelets Ratio as Predictive Markers of Progression and Prognosis in Patients with Non-Small Cell Lung Cancer.Open access Macedonian journal of medical sciences · 2018Article
- Plasma fibrinogen and serum albumin levels (FA score) act as a promising prognostic indicator in non-small cell lung cancer.OncoTargets and therapy · 2017Article
- NEUTROPHIL/LYMPHOCYTE RATIO AND PLATELET/LYMPHOCYTE RATIO IN PATIENTS WITH NSCLC.Materia socio-medica · 2016Article
- Preoperative platelet-lymphocyte ratio is superior to neutrophil-lymphocyte ratio as a prognostic factor for soft-tissue sarcoma.BMC cancer · 2015Article
- The clinical significance of preoperative plasma fibrinogen level and platelet count in resectable esophageal squamous cell carcinoma.World journal of surgical oncology · 2015Article
- MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3.Molecular cancer · 2015Article
- Prognostic role of elevated platelet count in patients with lung cancer: a systematic review and meta-analysis.International journal of clinical and experimental medicine · 2015Article
- Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase.Cell death & disease · 2014Article
- Prognostic significance of initial platelet counts and fibrinogen level in advanced non-small cell lung cancer.Journal of Korean medical science · 2014Article
- Preoperative thrombocytosis is a significant unfavorable prognostic factor for patients with resectable non-small cell lung cancer.World journal of surgical oncology · 2014Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung cancer (LC) is now the leading cause of cancer mortality in the world, therefore it would be useful to identify prognostic factors to determine patient outcome. The objective of this study is to evaluate the usefulness of platelet counts at the time of diagnosis as a prognostic factor. A retrospective study of patients with histological diagnostic evidence of LC was carried in our catchment area over a 3-year period. Survival adjusted for other factors was assessed according to the platelet count at the time of diagnosis. Patients with platelet levels within the reference range (RR) (135000-381000/microl) were divided into two groups, between 135000-258000/microl and 258000-381000/microl. A third group was made up of patients with platelet counts over 381000/microl. Adjusted survival was analysed using Cox regression models. Patients with high platelets have a 37% worse survival than those with a platelet level within the RR, but lower than 258000/microl. When tumour stage is included in the covariates, platelet levels are no longer an independent survival factor. In conclusion, platelet levels at the time of diagnosis could be a useful prognostic factor in LC.
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