Evidence map›Paper›PMID 19381477›Full record

ArticleFolia microbiologica2008

The selection of single-chain Fv antibody fragments specific to Bhlp 29.7 protein of Brachyspira hyodysenteriae.

D Lobová, A Cízek, V Celer

Abstract read
PubMed Publisher
In one paragraph

Article in Folia microbiologica, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Recombinant Antibodies in Veterinary Medicine: An Update.Frontiers in veterinary science · 2018
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D LobováInstitute of Microbiology and Immunology, Veterinary and Pharmaceutical University Brno, Czech Republic.
A Cízek
V Celer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-chain antibodies (scFv) specific to Brachyspira hyodysenteriae were isolated from a phagemid library. Recombinant Bhlp 29.7 protein was used for scFv selection and individual clones were tested by ELISA and immunofluorescent test; four unique clones were isolated. One of selected clones was able to bind specifically B. hyodysenteriae in ELISA and immunofluorescence test. This is the first report of species-specific recombinant antibodies against B. hyodysenteriae.

Indexed as

AnimalsAntibodies, BacterialAntibodies, MonoclonalAntibody SpecificityAntigens, BacterialBacterial ProteinsBrachyspira hyodysenteriaeEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, DirectGram-Negative Bacterial InfectionsImmunoglobulin Variable RegionLipoproteinsPeptide LibraryRecombinant Fusion ProteinsSpecies SpecificitySwineAntibodies, BacterialAntibodies, MonoclonalAntigens, BacterialBacterial ProteinsImmunoglobulin Variable RegionLipoproteinsPeptide LibraryRecombinant Fusion Proteins

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.