Evidence map›Paper›PMID 19381353›Full record

ArticleJournal of applied physics2007

Experimentally validated quantitative linear model for the device physics of elastomeric microfluidic valves.

Emil P Kartalov, Axel Scherer, Stephen R Quake, Clive R Taylor, W French Anderson

Abstract read
In one paragraph

Article in Journal of applied physics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emil P Kartalov
Axel Scherer
Stephen R Quake
Clive R Taylor
W French Anderson

Funding

Ultrasensitive Nanofluidic Devices for Genomic AnalysisR01HG002644 · NHGRI · STANFORD UNIVERSITY · PI QUAKE, STEPHEN R · 2004 to 2008
$5.1M
Integrated Nanofluidic BioMEMS for Biomedical Diagnostics and AnalysisK99EB007151 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KARTALOV, EMIL P · 2007 to 2008
$178k
NHGRI NIH HHS R01 HG002644NIBIB NIH HHS K99 EB007151
6 · The paper itself

Abstract

A systematic experimental study and theoretical modeling of the device physics of polydimethylsiloxane "pushdown" microfluidic valves are presented. The phase space is charted by 1587 dimension combinations and encompasses 45-295 μm lateral dimensions, 16-39 μm membrane thickness, and 1-28 psi closing pressure. Three linear models are developed and tested against the empirical data, and then combined into a fourth-power-polynomial superposition. The experimentally validated final model offers a useful quantitative prediction for a valve's properties as a function of its dimensions. Typical valves (80-150 μm width) are shown to behave like thin springs.

Identifiers

PMID19381353
PMCPMC2670093

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.