ArticleBiometrika2008
Nonparametric variance estimation in the analysis of microarray data: a measurement error approach.
Article in Biometrika, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Article
- Simultaneous treatment of unspecified heteroskedastic model error distribution and mismeasured covariates for restricted moment models.Journal of econometrics · 2017Article
- Simulation-Extrapolation with Latent Heteroskedastic Error Variance.Psychometrika · 2017Article
- Assessment of bias in experimentally measured diffusion tensor imaging parameters using SIMEX.Magnetic resonance in medicine · 2013Article
- NONPARAMETRIC ESTIMATION OF GENEWISE VARIANCE FOR MICROARRAY DATA.Annals of statistics · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
This article investigates the effects of measurement error on the estimation of nonparametric variance functions. We show that either ignoring measurement error or direct application of the simulation extrapolation, SIMEX, method leads to inconsistent estimators. Nevertheless, the direct SIMEX method can reduce bias relative to a naive estimator. We further propose a permutation SIMEX method which leads to consistent estimators in theory. The performance of both SIMEX methods depends on approximations to the exact extrapolants. Simulations show that both SIMEX methods perform better than ignoring measurement error. The methodology is illustrated using microarray data from colon cancer patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.