Evidence map›Paper›PMID 19380076›Full record

ArticlePediatric neurology2009

Isolated cranial nerve enhancement in metachromatic leukodystrophy.

Rani K Singh, Robert T Leshner, Nadja Kadom, Adeline L Vanderver

Open access · greenAbstract readCase Reports
In one paragraph

Article in Pediatric neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Pathology of the neurovascular unit in leukodystrophies.Acta neuropathologica communications · 2021
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rani K SinghDepartment of Neurology, Children's National Medical Center, Washington, DC 20010, USA.
Robert T Leshner
Nadja Kadom
Adeline L Vanderver
Children's National · US

Funding

Molecular Mechanisms in Vanishing White Matter DiseaseK08NS060695 · NINDS · CHILDREN'S RESEARCH INSTITUTE · PI VANDERVER, ADELINE LUCIE · 2009 to 2013
$643k
NINDS NIH HHS K08 NS060695
6 · The paper itself

Abstract

Metachromatic leukodystrophy is a lysosomal storage disorder with an estimated incidence of 1:40,000. Magnetic resonance imaging at time of diagnosis often shows symmetric white matter involvement, sparing the arcuate fibers. A 25-month-old female child presented with a cranial neuropathy, a spastic gait, decreased leukocyte arylsulfatase-A activity, and elevated urinary sulfatides. Magnetic resonance imaging revealed multiple cranial nerve enhancement, without intraparenchymal white matter involvement.

Indexed as

BrainChild, PreschoolCranial Nerve DiseasesCranial NervesDiagnosis, DifferentialFemaleHumansLeukodystrophy, MetachromaticMagnetic Resonance Imaging

Identifiers

PMID19380076
PMCPMC2705062
OpenAlexW2085678420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.