Evidence map›Paper›PMID 19379708›Full record

ArticleBiochemical and biophysical research communications2009

Microtubule-independent regulation of neurofilament interactions in vitro by neurofilament-bound ATPase activities.

J F Leterrier, P A Janmey, J Eyer

Abstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J F LeterrierDpt Neurosciences, UMR CNRS 6187, PBS, Universite de Poitiers, Poitiers Cedex, France. jean.francois.leterrier@univ-poitiers.fr
P A Janmey
J Eyer

Funding

Mechanical control of cell growth and differentiationR01GM083272 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI JANMEY, PAUL A · 2008 to 2011
$2.0M
NIGMS NIH HHS R01 GM083272
6 · The paper itself

Abstract

Neurofilaments (NFs), the major neuronal intermediate filaments, form networks in vitro that mimic the axonal NF bundles. This report presents evidence for previously unknown regulation of the interactions between NFs by NF-associated ATPases. Two opposite effects on NF gelation in vitro occur at low and high ATP concentration. These findings support the hypothesis that NF bundles in situ are dynamic structures, and raise the possibility that ATP-hydrolyzing mechanoenzymes regulate their organization.

Indexed as

Adenosine TriphosphatasesAnimalsCattleIntermediate FilamentsMicrotubulesNeuronsRatsAdenosine Triphosphatases

Identifiers

PMID19379708
PMCPMC3118462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.