ReviewVeterinary research
Perpetuation of Leishmania: some novel insight into elegant developmental programs.
Review in Veterinary research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Proteins involved in the biosynthesis of lipophosphoglycan in Leishmania: a comparative genomic and evolutionary analysis.Parasites & vectors · 2020Article
- The site of the bite: Leishmania interaction with macrophages, neutrophils and the extracellular matrix in the dermis.Parasites & vectors · 2016Review
- Coinjection with TLR2 agonist Pam3CSK4 reduces the pathology of leishmanization in mice.PLoS neglected tropical diseases · 2015Article
- Large-scale investigation of Leishmania interaction networks with host extracellular matrix by surface plasmon resonance imaging.Infection and immunity · 2014Article
- Application of serial analysis of gene expression to the study of the gene expression profile of Leishmania infantum chagasi promastigote.Journal of biomedicine & biotechnology · 2012Article
- Kinetic analysis of ex vivo human blood infection by Leishmania.PLoS neglected tropical diseases · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leishmania spp. are polarized single-celled eukaryotic parasites, the perpetuation of which relies on two other organisms they "use" as hosts. One of the Leishmania host organisms is a blood-feeding female sand fly, the second host being a mammal that acts as a blood source for the female sand fly. Leishmania-hosting sand flies transmit the metacyclic promastigote developmental stage to the mammal skin. While many mammals are known to act as sand fly blood sources, only some of these mammals are/ will be "used" as Leishmania hosts. This host status means that skin as well as skin-distant tissues and cell lineages (mononuclear phagocytes and fibroblasts) of these mammals are rapidly and continuously remodelled as niches where Leishmania will deploy its developmental programs: it is noteworthy that without the deployment of the developmental program underlying Leishmania transmission from the mammal to the blood-searching and blood-feeding sand flies, the perpetuation of Leishmania will be suspended. While post genomic approaches are providing insight about some features of Leishmania major, Leishmania infantum/chagasi and Leishmania braziliensis, such approaches are not yet available for the natural hosts (wild rodents, wild sand flies) these Leishmania species "use" as hosts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.