Evidence map›Paper›PMID 19378187›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2009

Analysis of distant communication on defined chromatin templates in vitro.

Yury S Polikanov, Vasily M Studitsky

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Theoretical analysis of the role of chromatin interactions in long-range action of enhancers and insulators.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yury S PolikanovDepartment of Pharmacology, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA.
Vasily M Studitsky
Johnson University · US

Funding

Mechanism Transcript Elongation in ChromatinR01GM058650 · NIGMS · WAYNE STATE UNIVERSITY · PI STUDITSKY, VASILY M · 1999 to 2015
$4.7M
NIGMS NIH HHS GM58650NIGMS NIH HHS R01 GM058650
6 · The paper itself

Abstract

Regulation of many biological processes in eukaryotes involves distant communication between the regulatory DNA sequences (e.g., enhancers) and their targets over the DNA regions organized in chromatin. However previously developed methods for analysis of communication in chromatin in vitro are artifact-prone and/or do not allow analysis of communication on physiologically relevant, saturated arrays of nucleosomes. Here we describe a method for quantitative analysis of the rate of distant communication in cis on saturated arrays of nucleosomes capable of forming the 30-nm chromatin fibers in vitro.

Indexed as

AnimalsBuffersChickensChromatinChromatin Assembly and DisassemblyDNADNA PrimersDNA Restriction EnzymesElectrophoresisEnhancer Elements, GeneticIndicators and ReagentsMolecular BiologyNucleosomesPromoter Regions, GeneticRNATemplates, GeneticBuffersChromatinDNADNA PrimersDNA Restriction EnzymesIndicators and ReagentsNucleosomesRNA

Identifiers

PMID19378187
PMCPMC5100816
OpenAlexW2400158735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.