ArticleInfection and immunity1991
Identification of monoclonal antibody-binding domains within antigen P1 of Streptococcus mutans and cross-reactivity with related surface antigens of oral streptococci.
Article in Infection and immunity, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 41 citations in OpenAlex.
- The structure ofInfection and immunity · 2026Article
- Amyloid Aggregates Are Localized to the Nonadherent Detached Fraction of Aging Streptococcus mutans Biofilms.Microbiology spectrum · 2022Article
- Characterization of an intermolecular quaternary interaction between discrete segments of the Streptococcus mutans adhesin P1 by NMR spectroscopy.The FEBS journal · 2020Article
- Diversity of SpaP in genetic and salivary agglutinin mediated adherence among Streptococcus mutans strains.Scientific reports · 2019Article
- Specific binding of a naturally occurring amyloidogenic fragment of Streptococcus mutans adhesin P1 to intact P1 on the cell surface characterized by solid state NMR spectroscopy.Journal of biomolecular NMR · 2016Article
- Identification of a supramolecular functional architecture of Streptococcus mutans adhesin P1 on the bacterial cell surface.The Journal of biological chemistry · 2015Article
- Immunogenicity and in vitro and in vivo protective effects of antibodies targeting a recombinant form of the Streptococcus mutans P1 surface protein.Infection and immunity · 2014Article
- An intramolecular interaction involving the N terminus of a streptococcal adhesin affects its conformation and adhesive function.The Journal of biological chemistry · 2013Article
- BrpA is involved in regulation of cell envelope stress responses in Streptococcus mutans.Applied and environmental microbiology · 2012Article
- The changing faces of Streptococcus antigen I/II polypeptide family adhesins.Molecular microbiology · 2010Review
- Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Requirements for surface expression and function of adhesin P1 from Streptococcus mutans.Infection and immunity · 2008Article
- Redirecting the humoral immune response against Streptococcus mutans antigen P1 with monoclonal antibodies.Infection and immunity · 2004Article
- Contribution of the alanine-rich region of Streptococcus mutans P1 to antigenicity, surface expression, and interaction with the proline-rich repeat domain.Infection and immunity · 2004Article
- Characterization of the Streptococcus mutans P1 epitope recognized by immunomodulatory monoclonal antibody 6-11A.Infection and immunity · 2004Article
- Identification of a point mutation resulting in loss of cell wall anchoring activity of SrtA of Streptococcus mutans NG5.Infection and immunity · 2004Article
- Further characterization of immunomodulation by a monoclonal antibody against Streptococcus mutans antigen P1.Infection and immunity · 2004Article
- Structural and functional variation within the alanine-rich repetitive domain of streptococcal antigen I/II.Infection and immunity · 2002Article
- Monoclonal antibody-mediated modulation of the humoral immune response against mucosally applied Streptococcus mutans.Infection and immunity · 2000Article
- Virulence of a spaP mutant of Streptococcus mutans in a gnotobiotic rat model.Infection and immunity · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Eleven monoclonal antibodies (MAbs) specific for P1, the major protein surface antigen of Streptococcus mutans serotype c, were characterized by Western blot (immunoblot) analysis and by radioimmunoassay using whole bacterial cells. The approximate binding domains of the MAbs were determined by using full-length and truncated P1 polypeptides. The accessibility of these binding sites on the surfaces of intact bacteria was determined by radioimmunoassay. The ability of each MAb to cross-react with related proteins from strains of S. mutans serotypes e and f, S. sanguis, and S. sobrinus serotype g is also reported.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.