Evidence map›Paper›PMID 19376855›Full record

ArticleJournal of bacteriology2009

The Escherichia coli mismatch repair protein MutL recruits the Vsr and MutH endonucleases in response to DNA damage.

Yaroslava Y Polosina, Justin Mui, Photini Pitsikas, Claire G Cupples

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yaroslava Y PolosinaDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.
Justin Mui
Photini Pitsikas
Claire G Cupples
Luminex (Canada) · CAUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activities of the Vsr and MutH endonucleases of Escherichia coli are stimulated by MutL. The interaction of MutL with each enzyme is enhanced in vivo by 2-aminopurine treatment and by inactivation of the mutY gene. We hypothesize that MutL recruits the endonucleases to sites of DNA damage.

Indexed as

DNA DamageAdenosine TriphosphatasesDNA-Binding ProteinsDNA Mismatch RepairDNA Repair EnzymesEndodeoxyribonucleasesEscherichia coliEscherichia coli ProteinsMutL ProteinsProtein BindingAdenosine TriphosphatasesDNA-Binding ProteinsDNA Repair EnzymesEndodeoxyribonucleasesEscherichia coli Proteinsmethyl-directed mismatch repair protein, E coliMutL protein, E coliMutL Proteinsvsr endonuclease

Identifiers

PMID19376855
PMCPMC2698396
OpenAlexW2169460602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.