ArticleCurrent biology : CB2009
In vivo detection of residues required for ligand-selective activation of the S-locus receptor in Arabidopsis.
Article in Current biology : CB, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- From recognition to response: integrated signaling pathways determining pollen acceptance and rejection in Brassicaceae.The New phytologist · 2026Review
- Self-incompatibility phenotypes of SRK mutants can be predicted with high accuracy.bioRxiv : the preprint server for biology · 2024Article
- Stop and go signals at the stigma-pollen interface of the Brassicaceae.Plant physiology · 2023Article
- Live-cell imaging of early events following pollen perception in self-incompatible Arabidopsis thaliana.Journal of experimental botany · 2020Article
- High temperature causes breakdown of S haplotype-dependent stigmatic self-incompatibility in self-incompatible Arabidopsis thaliana.Journal of experimental botany · 2019Article
- Review
- Activation of Self-Incompatibility Signaling in TransgenicG3 (Bethesda, Md.) · 2018Article
- Plant Lectins and Lectin Receptor-Like Kinases: How Do They Sense the Outside?International journal of molecular sciences · 2017Review
- Structural basis for specific self-incompatibility response in Brassica.Cell research · 2016Article
- In vivo imaging of the S-locus receptor kinase, the female specificity determinant of self-incompatibility, in transgenic self-incompatible Arabidopsis thaliana.Annals of botany · 2015Article
- Site-specific N-glycosylation of the S-locus receptor kinase and its role in the self-incompatibility response of the brassicaceae.The Plant cell · 2014Article
- Exploring the role of a stigma-expressed plant U-box gene in the pollination responses of transgenic self-incompatible Arabidopsis thaliana.Plant reproduction · 2014Article
- Self-incompatibility in Brassicaceae crops: lessons for interspecific incompatibility.Breeding science · 2014Review
- In planta assessment of the role of thioredoxin h proteins in the regulation of S-locus receptor kinase signaling in transgenic Arabidopsis.Plant physiology · 2013Article
- Molecular characterization and evolution of self-incompatibility genes in Arabidopsis thaliana: the case of the Sc haplotype.Genetics · 2013Article
- Self-incompatibility.F1000 biology reports · 2010Article
- Arabidopsis thaliana pattern recognition receptors for bacterial elongation factor Tu and flagellin can be combined to form functional chimeric receptors.The Journal of biological chemistry · 2010Article
- Arabidopsis and relatives as models for the study of genetic and genomic incompatibilities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Review
- Progress and Promise in using Arabidopsis to Study Adaptation, Divergence, and Speciation.The arabidopsis book · 2010Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The self-incompatibility response of crucifers is a barrier to fertilization in which arrest of pollen tube development is mediated by allele-specific interactions between polymorphic receptors and ligands encoded by the S-locus haplotype. Activation of stigma-expressed S-locus receptor kinase (SRK) [1] by pollen coat-localized S-locus cysteine-rich (SCR) ligand [2-5] and the resulting rejection of pollen occurs only if receptor and ligand are encoded by the same S haplotype [4, 6-8]. To identify residues within the SRK extracellular domain (eSRK) that are required for its ligand-selective activation, we assayed chimeric receptors and receptor variants containing substitutions at polymorphic sites in Arabidopsis thaliana[9, 10]. We show that only a small number of the approximately 100 polymorphic residues in eSRK are required for ligand-specific activation of self-incompatibility in vivo. These essential residues occur in two noncontiguous clusters located at equivalent positions in the two variants tested. They also correspond to sites showing elevated levels of substitutions in other SRKs, suggesting that these residues could define self-incompatibility specificity in most SRKs. The results demonstrate that the majority of eSRK residues that show signals of positive selection and previously surmised to function as specificity determinants are not essential for specificity in the SRK-SCR interaction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.