ReviewHarvard review of psychiatry2009
Reproductive aging, sex steroids, and mood disorders.
Review in Harvard review of psychiatry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Characterizing the spectrum of distress symptoms in midlife women with perimenopausal depression.Journal of affective disorders · 2026Trial
- Exploring heterogeneity of perimenopause with application of multivariable analysis approaches.BMC women's health · 2024Article
- Impact of Menopause in Patients with Multiple Sclerosis: Current Perspectives.International journal of women's health · 2023Review
- The Swiss Perimenopause Study - study protocol of a longitudinal prospective study in perimenopausal women.Women's midlife health · 2020Article
- The role of family history of depression and the menopausal transition in the development of major depression in midlife women: Study of women's health across the nation mental health study (SWAN MHS).Depression and anxiety · 2017Article
- Review: Puberty as a time of remodeling the adult response to ovarian hormones.The Journal of steroid biochemistry and molecular biology · 2016Review
- Regulation of the mouse medial prefrontal cortical synapses by endogenous estradiol.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Article
- Menopause in multiple sclerosis: therapeutic considerations.Journal of neurology · 2014Review
- Effects of SCH-23390 in combination with a low dose of 17β-estradiol on anxiety-like behavior in ovariectomized rats.BioMed research international · 2014Article
- Synaptic regulation of affective behaviors; role of BDNF.Neuropharmacology · 2014Review
- Female reproductive life cycle and hormones: methodology to improve clinical trials.The Journal of clinical psychiatry · 2013Article
- Enduring influence of pubertal stressors on behavioral response to hormones in female mice.Hormones and behavior · 2013Review
- Effects of social housing on hippocampal dendrites and behavior in ovariectomized rats.Brain research bulletin · 2013Article
- Sex differences, gonadal hormones and the fear extinction network: implications for anxiety disorders.Biology of mood & anxiety disorders · 2012Article
- Accelerated ovarian failure: a novel, chemically induced animal model of menopause.Brain research · 2011Review
- Estrogen therapy and cognition: a review of the cholinergic hypothesis.Endocrine reviews · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Epidemiologic studies have documented that the majority of women do not become depressed during the menopause transition. However, recent longitudinal studies suggest that in some women, the events related to the menopause transition could play a role in the onset of depression. In this article we review evidence suggesting a relationship between the menopause transition and depression. Additionally, we describe several findings that suggest a role of ovarian hormones in the onset of these depressions, including the clustering of episodes of depression during the stage of the menopause transition that is accompanied by estradiol withdrawal, and the therapeutic effects of short-term estradiol in depressed perimenopausal women. Finally, we discuss possible causes of affective disturbances during the menopause transition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.