ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009
Three-dimensional conformal radiation therapy for ependymoma.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Emotional and behavioral functioning after conformal radiation therapy for pediatric ependymoma.International journal of radiation oncology, biology, physics · 2014Trial
- Spinal ependymoma: a comprehensive review of molecular classification, management guidelines, and clinical outcomes with a focus on the pediatric population (Part III of ependymomas across compartments).Journal of neuro-oncology · 2026Review
- Review and update on pediatric ependymoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.Pediatric blood & cancer · 2023Article
- Article
- Case-based review: ependymomas in adults.Neuro-oncology practice · 2018Review
- Management of hydrocephalus in pediatric metastatic tumors of the posterior fossa at presentation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Pencil beam scanning proton therapy for pediatric intracranial ependymoma.Journal of neuro-oncology · 2016Article
- Long-Term Neurocognitive Functioning and Social Attainment in Adult Survivors of Pediatric CNS Tumors: Results From the St Jude Lifetime Cohort Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016Article
- Pulmonary Function After Treatment for Embryonal Brain Tumors on SJMB03 That Included Craniospinal Irradiation.International journal of radiation oncology, biology, physics · 2015Article
- Improvement of therapeutic index for brain tumors with daily image guidance.Radiation oncology (London, England) · 2013Article
- Proton radiotherapy for pediatric central nervous system ependymoma: clinical outcomes for 70 patients.Neuro-oncology · 2013Article
- Distinct disease-risk groups in pediatric supratentorial and posterior fossa ependymomas.Acta neuropathologica · 2012Article
- Post-operative radiation improves survival in children younger than 3 years with intracranial ependymoma.Journal of neuro-oncology · 2011Article
- Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicity.Radiation oncology (London, England) · 2011Article
- Evaluating the incidence and utility of microscopic metastatic dissemination as diagnosed by lumbar cerebro-spinal fluid (CSF) samples in children with newly diagnosed intracranial ependymoma.Journal of neuro-oncology · 2011Article
- Brain tumors across the age spectrum: biology, therapy, and late effects.Seminars in radiation oncology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe application of conformal radiation therapy in the treatment of pediatric ependymoma is a success story resulting from advances in radiation therapy planning and delivery. These advances occurred at a time when clinical trial results confirmed that radiotherapy avoidance strategies were unsuccessful. DISCUSSION: Investigators have been keen to confirm the promise of newer radiation therapy methods even for the youngest children. When preliminary results suggested that high-dose focal irradiation could be safely administered through systematic targeting and that cognitive function could be preserved, investigators moved to include conformal therapy in the frontline management of children regardless of age. The results with postoperative conformal radiation therapy were further enhanced when neurosurgeons increased the rate of gross-total resection and recognized that second surgery could be safely accomplished after incomplete initial resection. With more than a decade of experience, the role of conformal radiation therapy in the treatment of childhood ependymoma has been firmly established as investigators consider new trials to increase disease control and improve functional outcomes.
Indexed as
Identifiers
19373477What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.