GuidelineAnesthesia and analgesia2009
Consensus statement: First International Workshop on Anesthetics and Alzheimer's disease.
Guideline in Anesthesia and analgesia, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Changes in Cerebral Gray Matter Volume and Postoperative Cognitive Dysfunction in Elderly Patients Following Sevoflurane Anesthesia (POCD-MRI)
Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Relationship between Surgery under General Anesthesia and the Development of Dementia: A Systematic Review and Meta-Analysis.BioMed research international · 2020Pooled it
- Exposure to general anesthesia and risk of Alzheimer's disease: a systematic review and meta-analysis.BMC geriatrics · 2011Pooled it
- Studies in rats of a target specific and reversible general anesthetic with a favorable safety profile.PloS one · 2025Article
- Association between preventive treatment for unruptured intracranial aneurysms and incident dementia: a nationwide population-based cohort study.Scientific reports · 2024Article
- Evaluation of the Effects of Repetitive Anaesthesia Administration on the Brain Tissues and Cognitive Functions of Rats with Experimental Alzheimer's Disease.Medicina (Kaunas, Lithuania) · 2024Article
- The Effects of Sevoflurane and Aβ Interaction on CA1 Dendritic Spine Dynamics and MEGF10-Related Astrocytic Synapse Engulfment.International journal of molecular sciences · 2024Article
- Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged AppMolecular brain · 2022Article
- The New Frontier of Perioperative Cognitive Medicine for Alzheimer's Disease and Related Dementias.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- The Effect of Ulinastatin to the Learning and Memory in Zebrafish.Neuromolecular medicine · 2021Article
- Predicting unconsciousness after propofol administration: qCON, BIS, and ALPHA band frequency power.Journal of clinical monitoring and computing · 2021Article
- Surgery Performed Under Propofol Anesthesia Induces Cognitive Impairment and Amyloid Pathology in ApoE4 Knock-In Mouse Model.Frontiers in aging neuroscience · 2021Article
- Dementia friendly dentistry for the periodontal patient. Part 2: ethical treatment planning and management.British dental journal · 2019Article
- Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment.CNS neuroscience & therapeutics · 2018Article
- Postoperative Outcomes in Primary Total Knee Arthroplasty Patients With Preexisting Cognitive Impairment: A Systematic Review.Geriatric orthopaedic surgery & rehabilitation · 2018Article
- Neuroprotective Role of Agmatine in Neurological Diseases.Current neuropharmacology · 2018Review
- Relationship between general anesthesia and Alzheimer disease: A protocol for a systematic review and meta-analysis.Medicine · 2017Article
- Critical role of P2X7 receptors in the neuroinflammation and cognitive dysfunction after surgery.Brain, behavior, and immunity · 2017Article
- A Novel Stress-Diathesis Model to Predict Risk of Post-operative Delirium: Implications for Intra-operative Management.Frontiers in aging neuroscience · 2017Article
- Association between changes in cerebral grey matter volume and postoperative cognitive dysfunction in elderly patients: study protocol for a prospective observational cohort study.BMC anesthesiology · 2016Observational
- Lasting impact of general anaesthesia on the brain: mechanisms and relevance.Nature reviews. Neuroscience · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 10 institutions in 2 countries.
Funding
Abstract
In order to review the current status of the potential relationship between anesthesia and Alzheimer's disease, a group of scientists recently met in Philadelphia for a full day of presentations and discussions. This special article represents a consensus view on the possible link between Alzheimer's disease and anesthesia and the steps required to test this more definitively.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.