Evidence map›Paper›PMID 19371474›Full record

ReviewCurrent urology reports2009

New and novel markers for prostate cancer detection.

Michael C Risk, Daniel W Lin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael C RiskDepartment of Urology, University of Washington Medical Center, Seattle, WA 98195, USA.
Daniel W Lin
University of Washington Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection and treatment of prostate cancer was dramatically altered with the advent of the prostate-specific antigen (PSA), and its usefulness particularly in following patients after radical prostatectomy is unquestioned. The ability of PSA to predict prostate cancer, and in particular clinically relevant prostate cancer, has come into doubt in recent years and has led to the search for better diagnostic markers for prostate cancer. Both serum and urine biomarkers are in various stages of development, and many of these have been discovered through progress in genomic and proteomic analysis. Some of these perform better in limited study than our current standards of diagnosis (ie, PSA and digital rectal examinations), and some have suggested the capacity to predict stage and likelihood of recurrence. Further study is needed to validate many of these markers, and the future of prostate cancer detection will likely lie in multiplex assays that test a number of markers concomitantly to assess prostate cancer risk.

Indexed as

Antigens, NeoplasmBiomarkers, TumorDiagnosis, DifferentialHumansMaleProstate-Specific AntigenProstatic NeoplasmsAntigens, NeoplasmBiomarkers, Tumorearly prostate cancer antigen-2, humanearly prostate cancer antigen, humanprostate cancer antigen 3, humanProstate-Specific Antigen

Identifiers

PMID19371474
OpenAlexW2056275150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.