Evidence map›Paper›PMID 19371435›Full record

ReviewEnvironmental health : a global access science source2009

Does traffic exhaust contribute to the development of asthma and allergic sensitization in children: findings from recent cohort studies.

Lennart Bråbäck, Bertil Forsberg

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Environmental health : a global access science source, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02852499 (SEPAGES), which is not on this map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02852499 unknown statusnot on this mapstarted 2014, after this paper: background citation

SEPAGES : Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health

TypeobservationalSponsorUniversity Hospital, GrenobleRan2014 to 2021Enrolled1,010ConditionsHealthy VolunteerArmsUrine sampling, Carry a GPS and BET, Carry pollution sensor, Sampling at the maternity, Self-questionnaires
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 154 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lennart BråbäckOccupational & Environmental Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden. lennart.braback@telia.com
Bertil Forsberg
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review was to assess the evidence from recent prospective studies that long-term traffic pollution could contribute to the development of asthma-like symptoms and allergic sensitization in children. We have reviewed cohort studies published since 2002 and found in PubMed in Oct 2008. In all, 13 papers based on data from 9 cohorts have evaluated the relationship between traffic exposure and respiratory health. All surveys reported associations with at least some of the studied respiratory symptoms. The outcome varied, however, according to the age of the child. Nevertheless, the consistency in the results indicates that traffic exhaust contributes to the development of respiratory symptoms in healthy children. Potential effects of traffic exhaust on the development of allergic sensitization were only assessed in the four European birth cohorts. Long-term exposure to outdoor air pollutants had no association with sensitization in ten-year-old schoolchildren in Norway. In contrast, German, Dutch and Swedish preschool children had an increased risk of sensitization related to traffic exhaust despite fairly similar levels of outdoor air pollution as in Norway. Traffic-related effects on sensitization could be restricted to individuals with a specific genetic polymorphism. Assessment of gene-environment interactions on sensitization has so far only been carried out in a subgroup of the Swedish birth cohort. Further genetic association studies are required and may identify individuals vulnerable to adverse effects from traffic-related pollutants. Future studies should also evaluate effects of traffic exhaust on the development and long term outcome of different phenotypes of asthma and wheezing symptoms.

Indexed as

AsthmaChildCohort StudiesEnvironmental ExposureHumansHypersensitivityRisk FactorsVehicle EmissionsVehicle Emissions

Identifiers

PMID19371435
PMCPMC2674435
OpenAlexW2065239984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.