ArticleWorld journal of gastroenterology2009
Prevalence of lactase persistent/non-persistent genotypes and milk consumption in a young population in north-west Russia.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 27 citations in OpenAlex.
- Comparison of Lactase Variant MCM6 -13910 C>T Testing and Self-report of Dairy Sensitivity in Patients With Irritable Bowel Syndrome.Journal of clinical gastroenterology · 2019Article
- Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis.World journal of hepatology · 2016Article
- Latitude, sunshine, and human lactase phenotype distributions may contribute to geographic patterns of modern disease: the inflammatory bowel disease model.Clinical epidemiology · 2014Article
- High prevalence of lactase non-persistence among indigenous nomadic Nenets, north-west Russia.International journal of circumpolar health · 2012Article
- Lactose intolerance: diagnosis, genetic, and clinical factors.Clinical and experimental gastroenterology · 2012Article
- Lactase non-persistent genotype influences milk consumption and gastrointestinal symptoms in Northern Russians.BMC gastroenterology · 2011Article
- Dairy intolerance syndrome in Iranian young adult.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2009Article
- Relation of the C/T-13910 LCT Polymorphism with Body Composition Measures and Their Modulation by Dairy Products in a Caucasian Men.American journal of men's healthArticle
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo estimate the prevalence of the lactase non-persistent genotype (C/C-13910) in a northern Russian population in accordance with ethnicity, and to evaluate self-reported milk consumption depending on lactase activity.
methodsBlood samples for genotyping lactase activity, defining the C/T-13910 variant by polymerase chain reaction, and direct sequencing were taken from 231 medical students of Russian origin aged 17-26 years. We analyzed milk product consumption by questionnaire which was specially designed for the estimation of milk consumption and abdominal complaints.
resultsWe found that the prevalence of the C/C-13190 genotype in the northern Russian population was 35.6%. The other genotypes nearby C/T-13910 and associated with lactase activity were not present in the study population. The consumption of milk among people with the non-persistent genotype tended to be lower than among the lactose tolerant subjects, but was not statistically significant.
conclusionAn investigation of the lactase persistent genotype in a northern Russian population has not been performed before. The genotype did not affect the consumption of milk products in this population which could be explained by low consumption of milk products among the entire study population.
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