SynthesisThe Cochrane database of systematic reviews2009
Haloperidol for the treatment of nausea and vomiting in palliative care patients.
Synthesis in The Cochrane database of systematic reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 7 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- 2016 Updated MASCC/ESMO consensus recommendations: Management of nausea and vomiting in advanced cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Pooled it
- Pharmacological interventions for pruritus in adult palliative care patients.The Cochrane database of systematic reviews · 2016Pooled it
- Haloperidol for the treatment of nausea and vomiting in palliative care patients.The Cochrane database of systematic reviews · 2015Pooled it
- Levomepromazine for nausea and vomiting in palliative care.The Cochrane database of systematic reviews · 2015Pooled it
- Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.The Cochrane database of systematic reviews · 2015Pooled it
- Droperidol for treatment of nausea and vomiting in palliative care patients.The Cochrane database of systematic reviews · 2014Pooled it
- [Treatment of nausea and vomiting with 5HT3 receptor antagonists, steroids, antihistamines, anticholinergics, somatostatinantagonists, benzodiazepines and cannabinoids in palliative care patients : a systematic review].Schmerz (Berlin, Germany) · 2012Pooled it
- Hospice agency characteristics associated with benzodiazepine and antipsychotic prescribing.Journal of the American Geriatrics Society · 2023Article
- Insomnia among Cancer Patients in the Real World: Optimising Treatments and Tailored Therapies.International journal of environmental research and public health · 2023Review
- Class side effects: decreased pressure in the lower oesophageal and the pyloric sphincters after the administration of dopamine antagonists, neuroleptics, anti-emetics, L-NAME, pentadecapeptide BPC 157 and L-arginine.Inflammopharmacology · 2017Article
- [Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review].Schmerz (Berlin, Germany) · 2012Review
- Treating nausea and vomiting in palliative care: a review.Clinical interventions in aging · 2011Review
Corrections and comments
- Updated by
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNausea and vomiting are common symptoms of patients with terminal, incurable illnesses and can be distressing.
objectivesThe primary objective of the review was to evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients. SEARCH STRATEGY: Several electronic databases were searched including CENTRAL, MEDLINE, EMBASE, CINAHL and AMED, using relevant search terms and synonyms. Handsearching complemented electronic searches (using reference lists of included studies, relevant chapters and review articles). There were no language restrictions imposed. Database searching was performed between 2nd and 16th September 2007. SELECTION CRITERIA: Studies considered for inclusion were randomised controlled trials (RCTs) of haloperidol for the treatment of nausea or vomiting, or both, in any setting. The studies had to be conducted with adults receiving palliative care or suffering from an incurable progressive medical condition. Studies where nausea or vomiting, or both, thought to be secondary to pregnancy or surgery were excluded. DATA COLLECTION AND ANALYSIS: Records from each of the electronic databases were imported into a bibliographic package and merged into a core database where titles, keywords and abstracts were inspected for relevance. If it was not possible to accept or reject an abstract with certainty, the full text of the article was obtained for further evaluation. The two review authors independently assessed studies in accordance with the inclusion criteria. There were no differences in opinion between authors with regard to assessment of studies. MAIN
resultsNo RCTs were identified meeting the inclusion criteria. Twenty-six studies were considered but all were excluded from the review. AUTHORS'
conclusionsWe did not identify any RCTs exploring the effectiveness of haloperidol for nausea and vomiting in palliative care patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.