Evidence map›Paper›PMID 19369355›Full record

ArticleJournal of virology2009

RuvB-like protein 2 is a suppressor of influenza A virus polymerases.

Satoshi Kakugawa, Masayuki Shimojima, Gabriele Neumann, Hideo Goto, Yoshihiro Kawaoka

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Differential roles of putative arginine fingers of AAAbioRxiv : the preprint server for biology · 2024
    Article
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  6. Influenza A Virus-Host Protein Interactions Control Viral Pathogenesis.International journal of molecular sciences · 2017
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Chaperone-like activity of the AAA+ proteins Rvb1 and Rvb2 in the assembly of various complexes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Satoshi KakugawaDivision of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokaneda, Minato-ku, Tokyo 108-8639, Japan.
Masayuki Shimojima
Gabriele Neumann
Hideo Goto
Yoshihiro Kawaoka
The University of Tokyo · JPNational Institute of Infectious Diseases · JPTokyo University of Science · JPUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pro- and eukaryotic cells, RuvB-like protein 2 (RBL2) resolves Holliday junction recombination intermediates. Here, we identified RBL2 as a suppressor of influenza A virus replication. Human RBL2 appears to interfere with the oligomerization of the viral nucleoprotein, a critical step in the assembly of viral replication complexes.

Indexed as

ATPases Associated with Diverse Cellular ActivitiesCarrier ProteinsCell LineDNA HelicasesGene Expression Regulation, ViralGene Knockdown TechniquesHumansInfluenza A virusNucleocapsid ProteinsProtein MultimerizationRNA-Binding ProteinsRNA-Dependent RNA PolymeraseRNA, ViralViral Core ProteinsVirus ReplicationATPases Associated with Diverse Cellular ActivitiesCarrier ProteinsDNA HelicasesNP protein, Influenza A virusNucleocapsid ProteinsRNA-Binding ProteinsRNA-Dependent RNA PolymeraseRNA, ViralRUVBL2 protein, humanViral Core Proteins

Identifiers

PMID19369355
PMCPMC2698547
OpenAlexW2098750917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.