ArticleJournal of virology2009
Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells.
Article in Journal of virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Chemistry-mediated synthetic virus-cell interaction as a generic approach to enhance gene delivery to mammalian cells.Molecular therapy. Advances · 2026Article
- Evidence of a tolerogenic vaccine against AIDS in the Chinese macaque prefigures a potential human vaccine.Archives of virology · 2021Review
- TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components.Molecular therapy. Nucleic acids · 2019Article
- Modeling HIV-1 Latency Using Primary CD4Journal of virology · 2019Article
- A 30-year journey of trial and error towards a tolerogenic AIDS vaccine.Archives of virology · 2018Review
- Inhibition of HIV early replication by the p53 and its downstream gene p21.Virology journal · 2018Article
- Article
- Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.PLoS pathogens · 2017Article
- HIV integration sites in latently infected cell lines: evidence of ongoing replication.Retrovirology · 2017Article
- HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-κB.Retrovirology · 2016Article
- The effects of cocaine on HIV transcription.Journal of neurovirology · 2016Review
- Article
- Mechanisms of HIV Transcriptional Regulation by Drugs of Abuse.Current HIV research · 2016Review
- Human immunodeficiency virus (HIV)-1 integration sites in viral latency.Current HIV/AIDS reports · 2015Review
- Cross-clade ultrasensitive PCR-based assays to measure HIV persistence in large-cohort studies.Journal of virology · 2014Article
- One-year follow-up of transgene expression by integrase-defective lentiviral vectors and their therapeutic potential in spinocerebellar ataxia model mice.Gene therapy · 2014Article
- Mucosal SIV Vaccines Comprising Inactivated Virus Particles and Bacterial Adjuvants Induce CD8(+) T-Regulatory Cells that Suppress SIV-Positive CD4(+) T-Cell Activation and Prevent SIV Infection in the Macaque Model.Frontiers in immunology · 2014Article
- Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection.Journal of leukocyte biology · 2013Article
- Article
- From reactivation of latent HIV-1 to elimination of the latent reservoir: the presence of multiple barriers to viral eradication.BioEssays : news and reviews in molecular, cellular and developmental biology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Until very recently, quiescent CD4(+) T cells were thought to be resistant to human immunodeficiency virus (HIV) infection. Subsequent studies, attempting to fully elucidate the mechanisms of resistance, showed that quiescent cells could become infected by HIV at low efficiency and form a latently infected population. In this study, we set out to identify the sites of viral integration and to assess the efficiency of the overall integration process in quiescent cells. Based on our results, HIV integration in quiescent CD4(+) T cells occurs in sites similar to those of their prestimulated counterparts. While site selections are similar, the integration process in quiescent cells is plagued by the formation of high levels of incorrectly processed viral ends and abortive two-long-terminal-repeat circles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.