ReviewJournal of the Formosan Medical Association = Taiwan yi zhi2009
Human coronaviruses 229E and NL63: close yet still so far.
Review in Journal of the Formosan Medical Association = Taiwan yi zhi, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 55 citations in OpenAlex.
- Multicenter analysis of epidemiological and clinical features of pediatric acute lower respiratory tract infections associated with common human coronaviruses in China, 2014-2019.Virology journal · 2023Article
- Article
- Evaluating the Virology and Evolution of Seasonal Human Coronaviruses Associated with the Common Cold in the COVID-19 Era.Microorganisms · 2023Review
- Aerosol transmission of human pathogens: From miasmata to modern viral pandemics and their preservation potential in the Anthropocene record.Geoscience frontiers · 2022Article
- A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro.Pharmaceuticals (Basel, Switzerland) · 2022Article
- A Novel Method to Reduce ELISA Serial Dilution Assay Workload Applied to SARS-CoV-2 and Seasonal HCoVs.Viruses · 2022Article
- Epitope-based peptide vaccine design and elucidation of novel compounds against 3C like protein of SARS-CoV-2.PloS one · 2022Article
- Therapeutic approaches in COVID-19 followed before arrival of any vaccine.Materials today. Proceedings · 2022Article
- Epidemiological and co-infection characteristics of common human coronaviruses in Shanghai, 2015-2020: a retrospective observational study.Emerging microbes & infections · 2021Observational
- Comparative genomic analysis reveals varying levels of mammalian adaptation to coronavirus infections.PLoS computational biology · 2021Article
- Article
- TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.PLoS pathogens · 2021Article
- The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways.PLoS pathogens · 2021Article
- The role of NO in COVID-19 and potential therapeutic strategies.Free radical biology & medicine · 2021Review
- Bat coronavirus phylogeography in the Western Indian Ocean.Scientific reports · 2020Article
- SARS-CoV-2: Camazotz's Curse.Medical journal, Armed Forces India · 2020Review
- Certainty of success: three critical parameters in coronavirus vaccine development.NPJ vaccines · 2020Review
- Development and Evaluation of a Multiplexed Immunoassay for Simultaneous Detection of Serum IgG Antibodies to Six Human Coronaviruses.Scientific reports · 2019Article
- Identification of Diverse Bat Alphacoronaviruses and Betacoronaviruses in China Provides New Insights Into the Evolution and Origin of Coronavirus-Related Diseases.Frontiers in microbiology · 2019Article
- Myeloablation-associated deletion of ORF4 in a human coronavirus 229E infection.NPJ genomic medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HCoV-NL63 and HCoV-229E are two of the four human coronaviruses that circulate worldwide. These two viruses are unique in their relationship towards each other. Phylogenetically, the viruses are more closely related to each other than to any other human coronavirus, yet they only share 65% sequence identity. Moreover, the viruses use different receptors to enter their target cell. HCoV-NL63 is associated with croup in children, whereas all signs suggest that the virus probably causes the common cold in healthy adults. HCoV-229E is a proven common cold virus in healthy adults, so it is probable that both viruses induce comparable symptoms in adults, even though their mode of infection differs. Here, we present an overview of the current knowledge on both human coronaviruses, focusing on similarities and differences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.