ReviewEndocrine reviews2009
Instructing an embryonic stem cell-derived oocyte fate: lessons from endogenous oogenesis.
Review in Endocrine reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- Lineage tracing of soma-to-primordial germ cell-like conversion in human tumor cell line.iScience · 2026Article
- Prenatal Silicon Dioxide Nanoparticles Exposure Reduces Female Offspring Fertility Without Affecting Males.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The foundational framework of tumors: Gametogenesis, p53, and cancer.Seminars in cancer biology · 2022Review
- Dissecting the initiation of female meiosis in the mouse at single-cell resolution.Cellular and molecular life sciences : CMLS · 2021Article
- Comparison of different in vitro differentiation conditions for murine female germline stem cells.Cell proliferation · 2019Article
- Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance.Cell discovery · 2018Article
- Activation of the germ-cell potential of human bone marrow-derived cells by a chemical carcinogen.Scientific reports · 2014Article
- Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules.Human molecular genetics · 2014Article
- Investigating the role of tbx4 in the female germline in mice.Biology of reproduction · 2013Article
- Embryonic stem cell-derived granulosa cells participate in ovarian follicle formation in vitro and in vivo.Reproductive sciences (Thousand Oaks, Calif.) · 2013Article
- An evolutionary perspective on adult female germline stem cell function from flies to humans.Seminars in reproductive medicine · 2013Review
- Aberrant gene expression and sexually incompatible genomic imprinting in oocytes derived from XY mouse embryonic stem cells in vitro.PloS one · 2013Article
- Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- The next (re)generation of ovarian biology and fertility in women: is current science tomorrow's practice?Fertility and sterility · 2012Review
- Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM (epithelial cell adhesion molecule) selection.The Journal of biological chemistry · 2012Article
- Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women.Nature medicine · 2012Article
- Spontaneous generation of germline characteristics in mouse fibrosarcoma cells.Scientific reports · 2012Article
- Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells.Human molecular genetics · 2011Article
- A concise review on epigenetic regulation: insight into molecular mechanisms.International journal of molecular sciences · 2011Review
- Transplantation directs oocyte maturation from embryonic stem cells and provides a therapeutic strategy for female infertility.Human molecular genetics · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Female reproductive potential is limited in the majority of species due to oocyte depletion. Because functional human oocytes are restricted in number and accessibility, a robust system to differentiate oocytes from stem cells would enable a thorough investigation of the genetic, epigenetic, and environmental factors affecting human oocyte development. Also, the differentiation of functional oocytes from stem cells may permit the success of human somatic cell nuclear transfer for reprogramming studies and for the production of patient-specific embryonic stem cells (ESCs). Thus, ESC-derived oocytes could ultimately help to restore fertility in women. Here, we review endogenous and ESC-derived oocyte development, and we discuss the potential and challenges for differentiating functional oocytes from ESCs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.