ArticleOptics express2009
Multiplexed force measurements on live cells with holographic optical tweezers.
Article in Optics express, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Advances and future trends in real-time precision optical control of chemical processes in live cells.Npj imaging · 2025Review
- New Insights into LINC00346 and its Role in Disease.Frontiers in cell and developmental biology · 2021Review
- Probing force in living cells with optical tweezers: from single-molecule mechanics to cell mechanotransduction.Biophysical reviews · 2019Review
- Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring.Biotechnology and bioengineering · 2019Review
- Indirect optical trapping using light driven micro-rotors for reconfigurable hydrodynamic manipulation.Nature communications · 2019Article
- Photonic force optical coherence elastography for three-dimensional mechanical microscopy.Nature communications · 2018Article
- Phagosomal transport depends strongly on phagosome size.Scientific reports · 2017Article
- Multiplexed fluctuation-dissipation-theorem calibration of optical tweezers inside living cells.The Review of scientific instruments · 2017Article
- Microfabricated tissues for investigating traction forces involved in cell migration and tissue morphogenesis.Cellular and molecular life sciences : CMLS · 2017Review
- Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium.Biophysical journal · 2017Article
- Local Arp2/3-dependent actin assembly modulates applied traction force during apCAM adhesion site maturation.Molecular biology of the cell · 2017Article
- Microtechnologies for studying the role of mechanics in axon growth and guidance.Frontiers in cellular neuroscience · 2015Review
- Cell signaling experiments driven by optical manipulation.International journal of molecular sciences · 2013Review
- Article
- Force mapping during the formation and maturation of cell adhesion sites with multiple optical tweezers.PloS one · 2013Article
- Single-cell nanosurgery.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Practical axial optical trapping.The Review of scientific instruments · 2012Article
- Magnetic tweezers-based force clamp reveals mechanically distinct apCAM domain interactions.Biophysical journal · 2012Article
- Cell stimulation with optically manipulated microsources.Nature methods · 2009Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We describe open-loop and closed-loop multiplexed force measurements using holographic optical tweezers. We quantify the performance of our novel video-based control system in a driven suspension of colloidal particles. We demonstrate our system's abilities with the measurement of the mechanical coupling between Aplysia bag cell growth cones and beads functionalized with the neuronal cell adhesion molecule, apCAM. We show that cells form linkages which couple beads to the underlying cytoskeleton. These linkages are intermittent, stochastic and heterogeneous across beads distributed near the leading edge of a single growth cone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.