ReviewPhysiology (Bethesda, Md.)2009
Erythrocytes: oxygen sensors and modulators of vascular tone.
Review in Physiology (Bethesda, Md.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
143 citing papers in PubMed, 316 citations in OpenAlex.
- Decreased arterial PO2, not O2 content, increases blood flow through intrapulmonary arteriovenous anastomoses at rest.The Journal of physiology · 2016Trial
- Vasoconstrictor responsiveness during hyperbaric hyperoxia in contracting human muscle.Journal of applied physiology (Bethesda, Md. : 1985) · 2013Trial
- Red Blood Cells Beyond Oxygen Transport: Dynamic Regulators, Disease Biomarkers and Therapeutic Platforms-A Narrative Review.International journal of molecular sciences · 2026Review
- Red Blood Cell Membrane Mechanics Using Discrete Exterior Calculus (DEC) and Optimization.International journal for numerical methods in biomedical engineering · 2026Article
- Mechanotransduction mechanisms in human erythrocytes: Fundamental physiology and clinical significance.Channels (Austin, Tex.) · 2025Review
- Erythrocytes as a Source of Exerkines.International journal of molecular sciences · 2025Review
- Recombinant-Chemosynthetic Biosensors for Probing Cell Surface Signaling of Red Blood Cells and Other Cells.Chemical & biomedical imaging · 2025Article
- Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia-reperfusion injury.Clinical and translational medicine · 2025Review
- Development of thin-film micro-outlets for spatially constraining local POFrontiers in physiology · 2025Article
- Hemoglobin as an oxygen gasoreceptor.Acta biochimica Polonica · 2025Review
- Effects of autoregulated and non-autoregulated blood flow restriction on vastus medialis oblique responses during low-load resistance exercise.Frontiers in sports and active living · 2025Article
- Hif1α-dependent mitochondrial acute ONature communications · 2024Article
- Review
- Modulating Nitric Oxide: Implications for Cytotoxicity and Cytoprotection.Antioxidants (Basel, Switzerland) · 2024Review
- Capillary oxygen regulates demand-supply coupling by triggering connexin40-mediated conduction: Rethinking the metabolic hypothesis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The conducted vasomotor response and the principles of electrical communication in resistance arteries.Physiological reviews · 2024Review
- Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent andJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Effects of hyperventilation on oxygenation, apnea breaking points, diving response, and spleen contraction during serial static apneas.European journal of applied physiology · 2023Article
- Detection of Biomarker Using Aptasensors to Determine the Type of Diabetes.Diagnostics (Basel, Switzerland) · 2023Review
- Nitric oxide mediated hypoxia dynamics in COVID-19.Nitric oxide : biology and chemistry · 2023Review
83 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Through oxygen-dependent release of the vasodilator ATP, the mobile erythrocyte plays a fundamental role in matching microvascular oxygen supply with local tissue oxygen demand. Signal transduction within the erythrocyte and microvessels as well as feedback mechanisms controlling ATP release have been described. Our understanding of the impact of this novel control mechanism will rely on the integration of in vivo experiments and computational models.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.