ArticleThe Journal of comparative neurology2009
Spatial representations of odorants in olfactory bulbs of rats and mice: similarities and differences in chemotopic organization.
Article in The Journal of comparative neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
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- Taste enhances the ability to express a preference for a congruent odor in rats.Behavioral neuroscience · 2024Article
- Pyrfume: A window to the world's olfactory data.Scientific data · 2024Article
- Article
- Odor encoding by signals in the olfactory bulb.Journal of neurophysiology · 2023Article
- An Evolutionary Microcircuit Approach to the Neural Basis of High Dimensional Sensory Processing in Olfaction.Frontiers in cellular neuroscience · 2021Article
- Olfactory Detection Thresholds for Primary Aliphatic Alcohols in Mice.Chemical senses · 2020Article
- Dynamic Impairment of Olfactory Behavior and Signaling Mediated by an Olfactory Corticofugal System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Spatiotemporal dynamics of odor responses in the lateral and dorsal olfactory bulb.PLoS biology · 2019Article
- Effect of early experience on neuronal and behavioral responses to con- and heterospecific odors in closely related Mus taxa: epigenetic contribution in formation of precopulatory isolation.BMC evolutionary biology · 2019Article
- Differential localization of NT-3 and TrpM5 in glomeruli of the olfactory bulb of mice.The Journal of comparative neurology · 2014Article
- Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats.Chemical senses · 2014Article
- Olfaction-inspired sensing using a sensor system with molecular recognition and optimal classification ability for comprehensive detection of gases.Sensors (Basel, Switzerland) · 2014Article
- Differential associative training enhances olfactory acuity in Drosophila melanogaster.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Cluster analysis of rat olfactory bulb responses to diverse odorants.Chemical senses · 2012Article
- Article
- Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice.PloS one · 2012Article
- Olfactory aversive conditioning alters olfactory bulb mitral/tufted cell glomerular odor responses.Frontiers in systems neuroscience · 2012Article
- Timing of neurogenesis is a determinant of olfactory circuitry.Nature neuroscience · 2011Article
- Glomerular activity patterns evoked by natural odor objects in the rat olfactory bulb are related to patterns evoked by major odorant components.The Journal of comparative neurology · 2010Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In previous studies, we mapped glomerular layer 2-deoxyglucose uptake evoked by hundreds of both systematically related and chemically distinct odorants in rat olfactory bulbs. To determine which principles of chemotopic organization revealed in these studies may be more fundamental and which may be more species typical, we now have characterized patterns of responses to 30 of these odorants in mice. We found that only a few odorants evoked their multiple foci of peak activity in exactly the same locations in the two species. In mice, as in rats, odorants that shared molecular features evoked overlapping patterns, but the locations of the feature-responsive domains often differed in rats and mice. In rats, increasing carbon number within a homologous series of aliphatic odorants is generally associated with rostral and ventral progressions of activity within domains responding to odorant functional group and/or hydrocarbon backbone. Such chemotopic progressions were not obvious in mice, which instead showed more abrupt differences in activated glomeruli within the domains for odorants differing by a single methylene group. Despite the differences, quantitative relationships between overall uptake patterns exhibited a similar organization with respect to odorant chemistry for the two species, probably as a result of partial overlaps of peak domains and more extensive overlaps in large, low-activity areas for rats and mice. We conclude that clustering responses to shared odorant features may be a general strategy for odor coding but that the specific locations of high-activity domains may be unique to a species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.