Evidence map›Paper›PMID 19363031›Full record

ReviewThe Journal of biological chemistry2009

Homeostatic and adaptive responses to zinc deficiency in Saccharomyces cerevisiae.

David J Eide

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Floral Development onPlants (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Nonsense-mediated mRNA decay and metal ion homeostasis and detoxification in Saccharomyces cerevisiae.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Copper Acts Synergistically With Fluconazole inFrontiers in microbiology · 2022
    Article
  19. Article
  20. [Analysis of clinical characteristics of fungal ball in unilateral maxillary sinus].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David J EideDepartment of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA. eide@nutrisci.wisc.edu

Funding

REGULATION OF CELLULAR ZINC HOMEOSTASISR01GM056285 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI EIDE, DAVID J · 1997 to 2022
$6.2M
Zinc Transporters and Intracellular Zinc TraffickingR01GM069786 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI EIDE, DAVID J · 2004 to 2007
$938k
NIGMS NIH HHS GM56285NIGMS NIH HHS GM69786NIGMS NIH HHS R01 GM056285NIGMS NIH HHS R01 GM069786
6 · The paper itself

Abstract

Zinc is an essential nutrient and serves as a structural or catalytic cofactor for many proteins. Thus, cells need mechanisms to maintain zinc homeostasis when available zinc supplies decrease. In addition, cells require other mechanisms to adapt intracellular processes to suboptimal levels of zinc. By exploring the transcriptional responses to zinc deficiency, studies of the yeast Saccharomyces cerevisiae have revealed both homeostatic and adaptive responses to low zinc. The Zap1 zinc-responsive transcription factor regulates several genes in yeast, and the identity of these genes has led to new insights regarding how cells respond to the stress of zinc deficiency.

Indexed as

HomeostasisBinding SitesGene Expression Regulation, FungalGenome, BacterialModels, BiologicalModels, GeneticMolecular ConformationProtein Structure, TertiarySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsTranscription, GeneticZincSaccharomyces cerevisiae ProteinsTranscription FactorsZAP1 protein, S cerevisiaeZinc

Identifiers

PMID19363031
PMCPMC2707215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.