Evidence map›Paper›PMID 19362649›Full record

ArticleMethods in enzymology2009

Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.

John E Cronan, Jacob Thomas

Abstract read
In one paragraph

Article in Methods in enzymology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The Evolution of Lipids from Solvents to Substrates.Annual review of biophysics · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. MarinePharmaceuticals (Basel, Switzerland) · 2026
    Article
  10. Article
  11. Article
  12. Switching the strict substrate specificities of the β-ketoacyl-acyl carrier protein synthases, FabH and BioZ.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Review
  14. Two putativeMicrobiology (Reading, England) · 2025
    Article
  15. Microbiology (Reading, England) · 2025
    Article
  16. Article
  17. Article
  18. Deep sequencing of 16mSystems · 2025
    Article
  19. Review
  20. Functional disparities of malonyl-ACP decarboxylase betweenApplied and environmental microbiology · 2025
    Article

103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John E CronanDepartment of Biochemistry, University of Illinois, Urbana, Illinois, USA.
Jacob Thomas

Funding

GENETIC APPROACHES TO REGULATION OF LIPID METABOLISMR01AI015650 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI CRONAN, JOHN E. · 1985 to 2022
$12.0M
NIAID NIH HHS R01 AI015650
6 · The paper itself

Abstract

This review presents the most thoroughly studied bacterial fatty acid synthetic pathway, that of Escherichia coli and then discusses the exceptions to the E. coli pathway present in other bacteria. The known interrelationships between the fatty acid and polyketide synthetic pathways are also assessed, mainly in the Streptomyces group of bacteria. Finally, we present a compendium of methods for analysis of bacterial fatty acid synthetic pathways.

Indexed as

BacteriaBacterial ProteinsFatty AcidsMacrolidesModels, BiologicalSignal TransductionBacterial ProteinsFatty AcidsMacrolides

Identifiers

PMID19362649
PMCPMC4095770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.