ReviewWorld journal of gastroenterology2009
Body weight, lifestyle, dietary habits and gastroesophageal reflux disease.
Review in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 3 syntheses or guidelines pooled it, 174 citations in OpenAlex.
- Association between physical activity and risk of gastroesophageal reflux disease: A systematic review and meta-analysis.Journal of sport and health science · 2024Pooled it
- Pooled it
- Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study.European journal of epidemiology · 2022Pooled it
- The impact of low-fat and full-fat dairy foods on symptoms of gastroesophageal reflux disease: an exploratory analysis based on a randomized controlled trial.European journal of nutrition · 2022Trial
- Effect of Dewaxed Coffee on Gastroesophageal Symptoms in Patients with GERD: A Randomized Pilot Study.Nutrients · 2022Trial
- First-week clinical responses to dexlansoprazole 60 mg and esomeprazole 40 mg for the treatment of grades A and B gastroesophageal reflux disease.World journal of gastroenterology · 2017Trial
- Weight loss can lead to resolution of gastroesophageal reflux disease symptoms: a prospective intervention trial.Obesity (Silver Spring, Md.) · 2013Trial
- Vitamin D and hyperparathyroidism in obesity.The Journal of clinical endocrinology and metabolism · 2011Trial
- Ecological co-burden patterns of GERD and asthma: a multi-method analysis of representative global regions.Frontiers in nutrition · 2026Article
- Healthy lifestyle as a protective factor against the risk of gastroesophageal reflux disease: Prospective population cohort analysis.PloS one · 2026Article
- Gastro-oesophageal reflux disease symptom subtypes and endoscopy findings: a retrospective, cross-sectional study from Southwestern Nigeria.BMC gastroenterology · 2025Article
- A retrospective analysis of the effects of moderate sedation on the degree of cardia exposure in overweight elderly patients.BMC anesthesiology · 2025Article
- Associations between socio-demographic factors, social functioning, and sleep quality among GERD patients in Syria: a cross-sectional study.BMC gastroenterology · 2025Article
- Adherence to global diet quality score in relation to gastroesophageal reflux disease and flatulence in Iranian adults.BMC public health · 2025Article
- Global, regional, and national burden of gastroesophageal reflux disease (1990-2021): age-period-cohort analysis and Bayesian projections.Frontiers in public health · 2025Article
- Physical Activity and Prevalence of Functional Dyspepsia in Adults: A Cross-Sectional Study.International journal of preventive medicine · 2025Article
- Metabolic dysfunction-associated steatotic liver disease and gastroesophageal reflux disease: a mendelian randomization study in European and East Asian populations.Frontiers in genetics · 2024Article
- Diets including Animal Food Are Associated with Gastroesophageal Reflux Disease.European journal of investigation in health, psychology and education · 2023Article
- Review
- Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While lifestyle modifications are currently used as first-line treatment for subjects with gastroesophageal reflux disease (GERD), the pathogenetic role of lifestyle factors and consequently, the efficacy of lifestyle measures is controversial. Our aim was to systematically review the pathogenetic link between overweight/obesity, dietary habits, physical activity and GERD, and the beneficial effect of specific recommended changes, by means of the available literature from the 1999 to the present. Obesity, in particular, abdominal obesity, plays a key role in determining GERD symptoms and complications through mechanical and metabolic effects. Controlled weight loss (by diet or surgery) is effective in improving GERD symptoms. No definitive data exist regarding the role of diet and, in particular, of specific foods or drinks, in influencing GERD clinical manifestations. Moderate physical activity seems to be beneficial for GERD, while vigorous activity may be dangerous in predisposed individuals. In conclusion, being obese/overweight and GERD-specific symptoms and endoscopic features are related, and weight loss significantly improves GERD clinical-endoscopic manifestations. The role of dietary behavior, mainly in terms of specific dietary components, remains controversial. Mild routine physical activity in association with diet modifications, i.e. a diet rich in fiber and low in fat, is advisable in preventing reflux symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.