Evidence map›Paper›PMID 19360687›Full record

ArticleAutism research : official journal of the International Society for Autism Research2008

The onset of autism: patterns of symptom emergence in the first years of life.

Sally Ozonoff, Kelly Heung, Robert Byrd, Robin Hansen, Irva Hertz-Picciotto

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  6. Review
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  11. Scene construction and autobiographical memory retrieval in autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2024
    Review
  12. Allelic heterogeneity and abnormal vesicle recycling inFrontiers in molecular neuroscience · 2024
    Article
  13. Article
  14. Article
  15. Autism Spectrum Disorder in 2023: A Challenge Still Open.Turkish archives of pediatrics · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sally OzonoffM.I.N.D. Institute, University of California-Davis, Sacramento, USA. sjozonoff@ucdavis.edu
Kelly Heung
Robert Byrd
Robin Hansen
Irva Hertz-Picciotto

Funding

THE CHARGE STUDY: CHILDHOOD AUTISM RISKS FROM GENETICS AND THE ENVIRONMENT - ADMINISTRATIVE SUPPLEMENTR01ES015359 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA · 2007 to 2019
$13.8M
Infants at Risk of Autism: A Longitudinal StudyR01MH068398 · NIMH · UNIVERSITY OF CALIFORNIA DAVIS · PI OZONOFF, SALLY · 2003 to 2013
$6.1M
NIEHS NIH HHS R01 ES015359NIMH NIH HHS R01 MH068398
6 · The paper itself

Abstract

Previous conceptualizations of autism have suggested that symptoms are evident either early in the first year of life or later in the second year, after a loss of previously acquired skills. New research suggests, however, that these two patterns do not capture all the different ways autism can emerge. For example, some children show a developmental plateau marked by failure to progress, while other children display mixed features, with both early delays and later losses evident. This article reviews the literature on autism onset, discusses problems with the traditional ways in which onset has been conceptualized, and provides recommendations for future research. We suggest that onset is better thought of as a dimensional process rather than dichotomous categories.

Indexed as

Early DiagnosisAge of OnsetAutistic DisorderHumansInfantSeverity of Illness Index

Identifiers

PMID19360687
PMCPMC2857525

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.