Evidence map›Paper›PMID 19359659›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2009

Optical and multimodality molecular imaging: insights into atherosclerosis.

Farouc A Jaffer, Peter Libby, Ralph Weissleder

Abstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. In Vivo Fluorescence Molecular Imaging Using Covalent Organic Nanosheets Without Labeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Systematic imaging in medicine: a comprehensive review.European journal of nuclear medicine and molecular imaging · 2021
    Review
  12. IL-1β in atherosclerotic vascular calcification: From bench to bedside.International journal of biological sciences · 2021
    Review
  13. Article
  14. Article
  15. Anti-atherogenic effects of CD36-targeted epigallocatechin gallate-loaded nanoparticles.Journal of controlled release : official journal of the Controlled Release Society · 2019
    Article
  16. Molecular Imaging of the Heart.Comprehensive Physiology · 2019
    Review
  17. Article
  18. Position Paper Computational Cardiology.IEEE journal of biomedical and health informatics · 2019
    Article
  19. Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Farouc A JafferCardiovascular Research Center and Cardiology Division, Center for Molecular Imaging Research, Brigham and Women's Hospital, Boston, Mass., USA. fjaffer@mgh.harvard.edu
Peter Libby
Ralph Weissleder

Funding

Translational Program of Excellence in NanotechnologyU01HL080731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2005 to 2009
$14.9M
Small Animal Imaging Resource GrantR24CA092782 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, RALPH · 2001 to 2006
$4.2M
MR imaging of myeloperoxidase activityR01HL078641 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, RALPH · 2004 to 2007
$1.5M
Howard Hughes Medical InstituteNCI NIH HHS R24 CA092782NCI NIH HHS R24-CA92782NHLBI NIH HHS R01 HL078641NHLBI NIH HHS R01-HL078641NHLBI NIH HHS U01 HL080731NHLBI NIH HHS UO1-HL080731
6 · The paper itself

Abstract

Imaging approaches that visualize molecular targets rather than anatomic structures aim to illuminate vital molecular and cellular aspects of atherosclerosis biology in vivo. Several such molecular imaging strategies stand ready for rapid clinical application. This review describes the growing role of in vivo optical molecular imaging in atherosclerosis and highlights its ability to visualize atheroma inflammation, calcification, and angiogenesis. In addition, we discuss advances in multimodality probes, both in the context of multimodal imaging as well as multifunctional, or "theranostic," nanoparticles. This review highlights particular molecular imaging strategies that possess strong potential for clinical translation.

Indexed as

Contrast MediaAnimalsAtherosclerosisDiagnostic ImagingHumansMiceNanoparticlesNeovascularization, PathologicPhotosensitizing AgentsSpectrometry, FluorescenceTomography, Optical CoherenceContrast MediaPhotosensitizing Agents

Identifiers

PMID19359659
PMCPMC2733228

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.