ArticleAfrican health sciences2008
Factors associated with carcinoma of the oesophagus at Mulago Hospital, Uganda.
Article in African health sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Environmental and life-style risk factors for esophageal squamous cell carcinoma in Africa: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Systematic review and meta-analysis of esophageal cancer in Africa: Epidemiology, risk factors, management and outcomes.World journal of gastroenterology · 2019Pooled it
- Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer.The Cochrane database of systematic reviews · 2017Pooled it
- Systematic review: epidemiology of oesophageal cancer in Sub-Saharan Africa.Malawi medical journal : the journal of Medical Association of Malawi · 2010Pooled it
- Article
- Correlates of the Stage of Esophageal Cancer at Diagnosis Among Patients: A Mixed-Methods Cross-Sectional Study.Cancer management and research · 2026Article
- Assessing cross-country inequalities in global burden of gastrointestinal cancers: slope and concentration index approach.Discover oncology · 2025Article
- Clinical features of upper gastrointestinal endoscopy in 3146 patients: a 9-year retrospective cohort study in Zanzibar Archipelago, Tanzania.African health sciences · 2023Article
- Clinicopathological characteristics and treatment outcomes of oesophageal cancer patients in Uganda.Ecancermedicalscience · 2023Article
- Drinking patterns, alcoholic beverage types, and esophageal cancer risk in Africa: a comprehensive systematic review and meta-analysis.Frontiers in oncology · 2023Review
- Endoscopic esophageal stenting for advanced esophageal cancer in Lubaga Hospital, Kampala, Uganda.BMC research notes · 2022Article
- The diagnostic upper GI endoscopy camp: a pilot for enhancing service provision and training in eastern Uganda.African health sciences · 2022Article
- Risk factors for oesophageal squamous cell carcinoma in Mozambique.Ecancermedicalscience · 2022Article
- Upper gastrointestinal endoscopy findings in Mbale Regional Referral Hospital, Eastern Uganda: a 10-year retrospective analysis.African health sciences · 2021Article
- Cancer in Africa: The Untold Story.Frontiers in oncology · 2021Article
- Cancer Risk Studies and Priority Areas for Cancer Risk Appraisal in Uganda.Annals of global health · 2020Review
- Indications and findings of upper gastrointestinal endoscopy in patients presenting to a District Hospital, Ghana.The Pan African medical journal · 2019Article
- Global Incidence and mortality of oesophageal cancer and their correlation with socioeconomic indicators temporal patterns and trends in 41 countries.Scientific reports · 2018Article
- Informing etiologic research priorities for squamous cell esophageal cancer in Africa: A review of setting-specific exposures to known and putative risk factors.International journal of cancer · 2017Review
- Population attributable fraction of Esophageal squamous cell carcinoma due to smoking and alcohol in Uganda.BMC cancer · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Uganda, as in many other parts of the world cancer of the oesophagus (CAE) is on the rise. Squamous cell carcinoma and adenocarcinoma are the common subtypes. Risk factors for this cancer have been identified but not studied systematically in Uganda. Identification of these factors would enable establishment of preventive measures.
objectiveTo determine the prevalence, histological features and associated factors for CAE among patients referred to the endoscopic unit of Mulago hospital, Kampala, Uganda.
methodsWe performed a 1-year cross-sectional study in 2004 and 2005 of all patients presenting for oesophageal-gastro-duodenoscopy (EGD) at Mulago Hospital. Demographic characteristics, behavioural practices, endoscopy findings and histology results where biopsies were performed were collected using a study tool. Data analysis was done using STATA 8 statistical package.
resultsTwo hundred nineteen patients were enrolled in the study, three were excluded because they could not tolerate the endoscopy procedure. Fifty five (19%) of the 287 had histologically proven CAE. Squamous cell carcinoma was found in 100% of tumours of the upper third, 91% middle third, and 73% lower third of the oesophagus. Four patients had a histological diagnosis of adenocarcinoma of the oesophagus. Factors that were associated with CAE included age (OR 1.63, CI 1.34-1.98, p value <0.001), smoking (OR 3.63, CI 1.82-7.23, p value <0.001) and gender (OR 2.17, CI 1.07-4.41, p value 0.032).
conclusionMany patients referred for EGD in Uganda had esophageal cancer most of which were.squamous cell type. Smoking, male gender and older age were risk factors. Preventive measures should target stopping smoking.
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Identifiers
19357755PMC2584326W2108764636What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.