ArticleJournal of clinical microbiology2009
Real-time quantitative PCR to determine chlamydial load in men and women in a community setting.
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Risk of pelvic inflammatory disease following Chlamydia trachomatis infection: analysis of prospective studies with a multistate model.American journal of epidemiology · 2013Pooled it
- Impact of Chlamydia trachomatis in the reproductive setting: British Fertility Society Guidelines for practice.Human fertility (Cambridge, England) · 2010Guideline
- Vaginal Swab vs Urine for Detection ofAnnals of family medicinePooled it
- Development and evaluation of dried urine strip for genital chlamydia and gonorrhea testing.Journal of clinical microbiology · 2026Article
- Multi-repeat sequences identification using genome mining techniques for developing highly sensitive molecular diagnostic assay for the detection ofOpen research Africa · 2024Article
- Surface enhanced Raman spectroscopy of Chlamydia trachomatis and Neisseria gonorrhoeae for diagnostics, and extra-cellular metabolomics and biochemical monitoring.Scientific reports · 2018Article
- Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study.Pathogens and disease · 2017Article
- Genital Chlamydia trachomatis Infections Clear More Slowly in Men Than Women, but Are Less Likely to Become Established.The Journal of infectious diseases · 2017Article
- Mobile nucleic acid amplification testing (mobiNAAT) for Chlamydia trachomatis screening in hospital emergency department settings.Scientific reports · 2017Article
- Leucocyte esterase dip-stick test as a point-of-care diagnostic for urogenital chlamydia in male patients: A multi-center evaluation in two STI outpatient clinics in Paramaribo and Amsterdam.BMC infectious diseases · 2016Article
- Chlamydia trachomatis genotypes in a cross-sectional study of urogenital samples from remote Northern and Central Australia.BMJ open · 2016Article
- Microbiological Characteristics of Chlamydia trachomatis and Neisseria gonorrhoeae Infections in South African Women.Journal of clinical microbiology · 2016Article
- Chlamydia trachomatis load in population-based screening and STI-clinics: implications for screening policy.PloS one · 2015Article
- Chlamydia detection during the menstrual cycle: a cross-sectional study of women attending a sexual health service.PloS one · 2014Article
- Effect of HIV and chlamydia infection on rectal inflammation and cytokine concentrations in men who have sex with men.Clinical and vaccine immunology : CVI · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We used a PCR method to quantify the loads of Chlamydia trachomatis organisms in self-collected urine and vulvovaginal swab (VVS) samples from 93 women and 30 men participating in the Chlamydia Screening Studies Project, a community-based study of individuals not seeking health care. For women, self-collected VVS had a higher mean chlamydial load (10,405 organisms/ml; 95% confidence interval [95% CI], 5,167 to 21,163 organisms/ml) than did first-void urines (FVU) (503 organisms/ml; 95% CI, 250 to 1,022 organisms/ml; P < 0.001). Chlamydial loads in female and male self-collected FVU specimens were similar (P = 0.634). The mean chlamydial load in FVU specimens decreased with increasing age in females and males. There was no strong statistical evidence of differences in chlamydial load in repeat male and female FVU specimens taken when patients attended for treatment a median of 23.5 (range, 14 to 62) and 28 (range, 13 to 132) days later, respectively, or in VVS taken a median of 35 (range, 14 to 217) days later. In this study, chlamydial load values for infected persons in the community who were not seeking treatment were lower than those published in other studies involving symptomatic patients attending clinical settings. This might have implications for estimates of the infectiousness of chlamydia. The results of this study provide a scientific rationale for preferring VVS to FVU specimens from women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.