Evidence map›Paper›PMID 19357167›Full record

ArticleJournal of virology2009

Characterization of Imjin virus, a newly isolated hantavirus from the Ussuri white-toothed shrew (Crocidura lasiura).

Jin-Won Song, Hae Ji Kang, Se Hun Gu, Sung Sil Moon, Shannon N Bennett, Ki-Joon Song, Luck Ju Baek, Heung-Chul Kim, Monica L O'Guinn, Sung-Tae Chong and 2 more

Abstract read
In one paragraph

Article in Journal of virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

  1. Pooled it
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jin-Won SongDepartment of Microbiology, College of Medicine, Institute for Viral Diseases and Bank for Pathogenic Viruses, Korea University, Seoul, Republic of Korea.
Hae Ji Kang
Se Hun Gu
Sung Sil Moon
Shannon N Bennett
Ki-Joon Song
Luck Ju Baek
Heung-Chul Kim
Monica L O'Guinn
Sung-Tae Chong
Terry A Klein
Richard Yanagihara
Korea University · KR59th Medical Wing · USUniversity of Hawaiʻi at Mānoa · US

Funding

WORLDWIDE EPIDEMIOLOGY &EPIZOOTIOLOGY OF HANTAVIRUSG12RR003061 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI OSTRANDER, GARY K · 1986 to 2011
$32.3M
UHI COBRE: P3: GROUP A STREPT IN RELATION TO ACUTE RHEUMATIC FEVER IN HAWAIIP20RR018727 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI HOANG, TUNG T · 2003 to 2011
$13.8M
Intraspecies Transmission and Infectivity of Insectivore-Borne HantavirusesR01AI075057 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI YANAGIHARA, RICHARD · 2008 to 2011
$1.5M
NCRR NIH HHS G12 RR003061NCRR NIH HHS G12RR003061NCRR NIH HHS P20 RR018727NCRR NIH HHS P20RR018727NIAID NIH HHS R01 AI075057NIAID NIH HHS R01AI075057
6 · The paper itself

Abstract

Until recently, the single known exception to the rodent-hantavirus association was Thottapalayam virus (TPMV), a long-unclassified virus isolated from the Asian house shrew (Suncus murinus). Robust gene amplification techniques have now uncovered several genetically distinct hantaviruses from shrews in widely separated geographic regions. Here, we report the characterization of a newly identified hantavirus, designated Imjin virus (MJNV), isolated from the lung tissues of Ussuri white-toothed shrews of the species Crocidura lasiura (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone in the Republic of Korea during 2004 and 2005. Seasonal trapping revealed the highest prevalence of MJNV infection during the autumn, with evidence of infected shrews' clustering in distinct foci. Also, marked male predominance among anti-MJNV immunoglobulin G antibody-positive Ussuri shrews was found, whereas the male-to-female ratio among seronegative Ussuri shrews was near 1. Plaque reduction neutralization tests showed no cross neutralization for MJNV and rodent-borne hantaviruses but one-way cross neutralization for MJNV and TPMV. The nucleotide and deduced amino acid sequences for the different MJNV genomic segments revealed nearly the same calculated distances from hantaviruses harbored by rodents in the subfamilies Murinae, Arvicolinae, Neotominae, and Sigmodontinae. Phylogenetic analyses of full-length S, M, and L segment sequences demonstrated that MJNV shared a common ancestry with TPMV and remained in a distinct out-group, suggesting early evolutionary divergence. Studies are in progress to determine if MJNV is pathogenic for humans.

Indexed as

PhylogenyAnimalsAntibodies, ViralAntigens, ViralChlorocebus aethiopsDNA, MitochondrialFemaleGenome, ViralKoreaMaleMicroscopy, Electron, TransmissionNeutralization TestsOrthohantavirusPrevalenceRNA, ViralSeasonsAntibodies, ViralAntigens, ViralDNA, MitochondrialRNA, Viral

Identifiers

PMID19357167
PMCPMC2687366
OpenAlexW2157783264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.