ArticleThe Plant cell2009
Suppression of repeat-mediated gross mitochondrial genome rearrangements by RecA in the moss Physcomitrella patens.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- Complete mitochondrial genome sequence of Koelreuteria paniculata (Sapindaceae) and comparative analysis within the family Sapindaceae.Scientific reports · 2026Article
- WHIRLY protein functions in plants.Food and energy security · 2023Review
- Chloroplastic RecA protein fromPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Assessment of Mitochondrial DNA Copy Number, Stability, and Repair in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2022Article
- The complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2022Article
- The complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2022Article
- The complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2022Article
- Ultra-deep sequencing reveals dramatic alteration of organellar genomes in Physcomitrella patens due to biased asymmetric recombination.Communications biology · 2021Article
- An Insight Into the Mechanism of Plant Organelle Genome Maintenance and Implications of Organelle Genome in Crop Improvement: An Update.Frontiers in cell and developmental biology · 2021Review
- The complete mitochondrial genome of Cycas debaoensis revealed unexpected static evolution in gymnosperm species.PloS one · 2021Article
- Holliday Junction Resolvase MOC1 Maintains Plastid and Mitochondrial Genome Integrity in Algae and Bryophytes.Plant physiology · 2020Article
- Factors Affecting Organelle Genome Stability inPlants (Basel, Switzerland) · 2020Review
- Article
- Structure-Function Analysis Reveals the Singularity of Plant Mitochondrial DNA Replication Components: A Mosaic and Redundant System.Plants (Basel, Switzerland) · 2019Review
- The complete mitochondrial genome of the early flowering plant Nymphaea colorata is highly repetitive with low recombination.BMC genomics · 2018Article
- RECX Interacts with Mitochondrial RECA to Maintain Mitochondrial Genome Stability.Plant physiology · 2018Article
- Dynamic Interplay between Nucleoid Segregation and Genome Integrity in Chlamydomonas Chloroplasts.Plant physiology · 2016Article
- The RECG1 DNA Translocase Is a Key Factor in Recombination Surveillance, Repair, and Segregation of the Mitochondrial DNA in Arabidopsis.The Plant cell · 2015Article
- Elevation of Pollen Mitochondrial DNA Copy Number by WHIRLY2: Altered Respiration and Pollen Tube Growth in Arabidopsis.Plant physiology · 2015Article
- RECG maintains plastid and mitochondrial genome stability by suppressing extensive recombination between short dispersed repeats.PLoS genetics · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
RecA and its ubiquitous homologs are crucial components in homologous recombination. Besides their eukaryotic nuclear counterparts, plants characteristically possess several bacterial-type RecA proteins localized to chloroplasts and/or mitochondria, but their roles are poorly understood. Here, we analyzed the role of the only mitochondrial RecA in the moss Physcomitrella patens. Disruption of the P. patens mitochondrial recA gene RECA1 caused serious defects in plant growth and development and abnormal mitochondrial morphology. Analyses of mitochondrial DNA in disruptants revealed that frequent DNA rearrangements occurred at multiple loci. Structural analysis suggests that the rearrangements, which in some cases were associated with partial deletions and amplifications of mitochondrial DNA, were due to aberrant recombination between short (<100 bp) direct and inverted repeats in which the sequences were not always identical. Such repeats are abundant in the mitochondrial genome, and interestingly many are located in group II introns. These results suggest that RECA1 does not promote but rather suppresses recombination among short repeats scattered throughout the mitochondrial genome, thereby maintaining mitochondrial genome stability. We propose that RecA-mediated homologous recombination plays a crucial role in suppression of short repeat-mediated genome rearrangements in plant mitochondria.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.