Evidence map›Paper›PMID 19356894›Full record

Trial reportThe Journal of arthroplasty2010

Clinical outcomes after simultaneous bilateral total knee arthroplasty: comparison to unilateral total knee arthroplasty and healthy controls.

Joseph A Zeni, Lynn Snyder-Mackler

Registry-linked trialOpen access · greenAbstract readClinical TrialComparative Study
In one paragraph

Trial report in The Journal of arthroplasty, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02349542 (The Safety of Liposomal Bupivacaine in Simultaneous Bilateral Total Knee Arthroplasty), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02349542 phase4completednot on this mapstarted 2015, after this paper: background citation

The Safety of Liposomal Bupivacaine in Simultaneous Bilateral Total Knee Arthroplasty

TypeinterventionalSponsorOrthoCarolina Research Institute, Inc.Ran2015 to 2016Enrolled20ConditionsArthroplasty, Replacement, Knee, PainArmsLiposomal bupivacaine
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Recovery after Total Knee Arthroplasty: Does one or two knees matter?Journal of clinical orthopaedics and trauma · 2025
    Article
  8. Article
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  10. Review
  11. Article
  12. Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joseph A ZeniDepartment of Physical Therapy, University of Delaware, Newark, Delaware 19716, USA.
Lynn Snyder-Mackler
University of Delaware · US

Funding

VALGUS BRACING FOR MEDIAL LAXITY IN PATIENTS WITH OSTEOARTHRITISP20RR016458 · NCRR · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2002 to 2011
$18.9M
NMES for Older Individuals After Total Knee ArthroplastyR01HD041055 · NICHD · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2002 to 2006
$1.4M
NCRR NIH HHS P20 RR016458NCRR NIH HHS P20RR016458NICHD NIH HHS R01 HD041055NICHD NIH HHS R01HD041055
6 · The paper itself

Abstract

The purpose of this study was to evaluate the functional outcomes of persons who underwent simultaneous bilateral total knee arthroplasty (TKA) compared to subjects who underwent unilateral TKA and a healthy control group. Fifteen subjects who underwent primary bilateral TKA and 15 sex, age, and body mass index-matched subjects who underwent primary unilateral TKA were observed prospectively for 2 years. Subjects in both surgical groups showed significant improvement in Knee Outcome Scores, Short Form 36 physical component scores, Timed Up and Go, and stair-climbing tasks (P <or= .004). No differences in final outcomes were found between surgical groups. In addition, most 2-year clinical measures were no different between the surgical and control groups. Subjects medically appropriate for bilateral TKA should be afforded this option.

Indexed as

AgedArthroplasty, Replacement, KneeFemaleHumansMaleMiddle AgedOsteoarthritis, KneeProspective StudiesRecovery of FunctionTreatment Outcome

Identifiers

PMID19356894
PMCPMC2876215
OpenAlexW1909393151

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.