Evidence map›Paper›PMID 19353709›Full record

ArticleClinical cardiology2009

Serum oxidative stress level correlates with clinical parameters in chronic systolic heart failure patients.

Offer Amir, Hagar Paz, Ori Rogowski, Marina Barshai, Moran Sagiv, Sergei Shnizer, Abraham Z Reznick, Ruthie E Amir

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Clinical cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  4. Oxidative stress and inflammatory markers - the future of heart failure diagnostics?Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Offer AmirDepartment of Cardiology, Lady Davis Carmel Medical Center, Haifa, Israel. ruthiea@wincol.ac.il
Hagar Paz
Ori Rogowski
Marina Barshai
Moran Sagiv
Sergei Shnizer
Abraham Z Reznick
Ruthie E Amir
Haifa Medical Center · ILWingate Institute · ILCarmel Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSerum oxidative stress (OS) level has an important role in the inflammatory process of heart failure. HYPOTHESIS: The study was designed to analyze serum OS levels in chronic heart failure (HF) patients and to examine the relation between OS levels and other clinical and prognostic parameters of HF.

methodsWe studied 82 consecutive chronic symptomatic HF patients with systolic LV dysfunction (ejection fraction <45%). The serum OS level was determined using thermochemiluminescence assay. We compared the serum OS levels with patients' clinical and prognostic parameters.

resultsHigher serum OS levels were associated with higher New York Heart Association class (P = .01), worse renal function (serum urea, creatinine, and creatinine clearance) (P<.001) and higher serum levels of hs-C-reactive protein and N-terminal pro brain natriuretic peptide (P = .001, P<.001, respectively).

conclusionsIn chronic systolic HF patients, high serum OS levels correlate with advanced disease and known markers of poor prognosis.

Indexed as

AgedAtrial Natriuretic FactorBiomarkersFemaleHeart Failure, SystolicHumansMaleOxidative StressPredictive Value of TestsPrognosisProtein PrecursorsSeverity of Illness IndexAtrial Natriuretic FactorBiomarkersN-terminal proatrial natriuretic peptideProtein Precursors

Identifiers

PMID19353709
PMCPMC6653550
OpenAlexW2072063657

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.