Evidence map›Paper›PMID 19352604›Full record

ArticleDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2009

[Predictive parameters in children with biliary atresia].

J Leonhardt, J F Kuebler, C Turowski, R von Wasielewski, E D Pfister, T Becker, B M Ure, C Petersen

Abstract readEnglish Abstract
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In one paragraph

Article in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J LeonhardtKlinik für Kinderchirurgie, Medizinische Hochschule, Hannover, Germany. Johannes_leonhardt@yahoo.de
J F Kuebler
C Turowski
R von Wasielewski
E D Pfister
T Becker
B M Ure
C Petersen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most children with biliary atresia require liver transplantation, and only about 20% survive in the long term with their native livers. Prognostic factors that determine disease progression are still lacking. This retrospective survey of 85 BA patients from 1993 to 2003 was aimed to evaluate prognostic factors using the log rank test. After 5 years 40% of the patients are alive with their native livers (35/85), 26 of them with normal bilirubin (31%). Age at Kasai operation (P=0.46), degree of liver fibrosis (P=0.95), and all laboratory test results before Kasai failed to correlate with outcome. Normal levels of bilirubin 3, 6, and 12 months after Kasai and of aspartate aminotransferase with gammaGT after 6 months are associated with survival with native liver. In conclusion our data demonstrate that a lack of predictive factors must prevent primary liver transplantation in BA patients.

Indexed as

AdolescentAlanine TransaminaseBiliary AtresiaBilirubinBiomarkersChildChild, PreschoolDisease ProgressionFemaleFollow-Up Studiesgamma-GlutamyltransferaseHumansInfantInfant, NewbornLiverLiver Cirrhosis, BiliaryAlanine TransaminaseBilirubinBiomarkersgamma-Glutamyltransferase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.