ArticlePloS one2009
Acute human self-poisoning with imidacloprid compound: a neonicotinoid insecticide.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 180 citations in OpenAlex.
- Neurotoxic Effects of Neonicotinoids on Mammals: What Is There beyond the Activation of Nicotinic Acetylcholine Receptors?-A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Effects of Neonicotinoid Pesticide Exposure on Human Health: A Systematic Review.Environmental health perspectives · 2017Pooled it
- Toxidromes.Nature reviews. Disease primers · 2026Review
- AI/ML-based computational models for toxicity prediction.Environmental science and pollution research international · 2026Review
- Postmortem distribution of thiamethoxam in biological fluids and solid tissues measured through liquid chromatography-tandem mass spectrometry using the standard addition method.Forensic toxicology · 2026Article
- Imidacloprid induces hepatorenal toxicity in male albino rats via oxidative, immune inflammatory, and proliferative effects: a 90-day study.Scientific reports · 2026Article
- Nanopesticides in Brazilian Crops: Classes, Mechanisms, Efficacy, Risks, and Photocatalytic Remediation.Plants (Basel, Switzerland) · 2025Review
- Article
- An unusual case of airway edema and encephalopathy: imidacloprid poisoning.World journal of emergency medicine · 2025Article
- Environmental contamination associated with biofuel production involving pesticide-coated seed corn as feedstock: a survey of community environmental and health impacts.Environmental health : a global access science source · 2025Article
- Treatment of an accident of imidacloprid poisoning.Frontiers in pharmacology · 2024Article
- Clinical Profile and Predictors of Intensive Care Admission in Neonicotinoid Poisoning in a Tertiary Care Hospital in South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Aiming for a Better Tomorrow.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Article
- The Protective Role of Oleuropein Aglycone against Pesticide-Induced Toxicity in a Human Keratinocytes Cell Model.International journal of molecular sciences · 2023Article
- Effects of exposure to imidacloprid contaminated feed on the visceral organs of adult male rabbits (Saudi journal of biological sciences · 2023Article
- Imidacloprid poisoning in a young female: a case report.Journal of medical case reports · 2023Article
- Article
- A Rare Presentation of Imidacloprid Poisoning.Cureus · 2023Article
- Microporous carbon for fast and simple electrochemical detection of imidacloprid insecticide in fruit and water samples.RSC advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundDeliberate self-poisoning with older pesticides such as organophosphorus compounds are commonly fatal and a serious public health problem in the developing world. The clinical consequences of self-poisoning with newer pesticides are not well described. Such information may help to improve clinical management and inform pesticide regulators of their relative toxicity. This study reports the clinical outcomes and toxicokinetics of the neonicotinoid insecticide imidacloprid following acute self-poisoning in humans. METHODOLOGY/PRINCIPAL
findingsDemographic and clinical data were prospectively recorded in patients with imidacloprid exposure in three hospitals in Sri Lanka. Blood samples were collected when possible for quantification of imidacloprid concentration. There were 68 patients (61 self-ingestions and 7 dermal exposures) with exposure to imidacloprid. Of the self-poisoning patients, the median time to presentation was 4 hours (IQR 2.3-6.0) and median amount ingested was 15 mL (IQR 10-50 mL). Most patients only developed mild symptoms such as nausea, vomiting, headache and diarrhoea. One patient developed respiratory failure needing mechanical ventilation while another was admitted to intensive care due to prolonged sedation. There were no deaths. Median admission imidacloprid concentration was 10.58 ng/L; IQR: 3.84-15.58 ng/L, Range: 0.02-51.25 ng/L. Changes in the concentration of imidacloprid in serial blood samples were consistent with prolonged absorption and/or saturable elimination.
conclusionsImidacloprid generally demonstrates low human lethality even in large ingestions. Respiratory failure and reduced level of consciousness were the most serious complications, but these were uncommon. Substitution of imidacloprid for organophosphorus compounds in areas where the incidence of self-poisoning is high may help reduce deaths from self-poisoning.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.