ArticleWorld journal of surgery2009
Intra-abdominal hypertension in acute pancreatitis.
Article in World journal of surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.
- Comparison of clinical outcomes between aggressive and non-aggressive intravenous hydration for acute pancreatitis: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Continuous Infusion of Fluid Hydration Over 24 Hours Does Not Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.Digestive diseases and sciences · 2022Trial
- Early enteral nutrition prevents intra-abdominal hypertension and reduces the severity of severe acute pancreatitis compared with delayed enteral nutrition: a prospective pilot study.World journal of surgery · 2013Trial
- Trial
- Early fluid therapy trajectories in acute pancreatitis: a retrospective cohort study.World journal of emergency surgery : WJES · 2025Article
- Predictive model for early fluid requirement in severe acute pancreatitis.BMC gastroenterology · 2025Observational
- Ascites characteristics in acute pancreatitis: A prognostic indicator of organ failure and mortality.World journal of gastroenterology · 2025Article
- Diagnosis and Management of Acute Pancreatitis.Diagnostics (Basel, Switzerland) · 2025Review
- Recent Treatment Strategies for Acute Pancreatitis.Journal of clinical medicine · 2024Review
- Early vs. late percutaneous catheter drainage of acute necrotic collections in patients with necrotizing pancreatitis.Abdominal radiology (New York) · 2023Article
- Severe Acute Pancreatitis Treated with Negative Pressure Wound Therapy System: Influence of Laboratory Markers.Journal of clinical medicine · 2023Article
- Article
- Abdominal Compartment Syndrome in Acute Pancreatitis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review.Annals of intensive care · 2022Review
- Intra-Abdominal Hypertension: A Systemic Complication of Severe Acute Pancreatitis.Medicina (Kaunas, Lithuania) · 2022Review
- Who would benefit from open abdomen in severe acute pancreatitis?-a matched case-control study.World journal of emergency surgery : WJES · 2021Article
- Computed tomography features predictive of intra-abdominal hypertension in acute necrotizing pancreatitis: A prospective study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- Ultrasound-Assisted versus Endoscopic Nasojejunal Tube Placement for Acute Pancreatitis: A Retrospective Feasibility Study.Gastroenterology research and practice · 2021Article
- Early intra-abdominal hypertension: A reliable bedside prognostic marker for severe acute pancreatitis.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of intra-abdominal hypertension (IAH) in patients with severe acute pancreatitis (SAP) is approximately 60-80%. It is usually an early phenomenon, partly related to the effects of the inflammatory process, causing retroperitoneal edema, fluid collections, ascites, and ileus, and partly iatrogenic, resulting from aggressive fluid resuscitation. It also can manifest at a later stage, often associated with local pancreatic complications. IAH is associated with impaired organ dysfunction, especially of the cardiovascular, respiratory, and renal systems. Using current definitions, the incidence of the clinical manifestation, abdominal compartment syndrome (ACS), has been reported as 27% in the largest study so far. Despite several intervention options, the mortality in patients developing ACS remains high: 50-75%. Prevention with judicious use of crystalloids is important, and nonsurgical interventions, such as nasogastric decompression, short-term use of neuromuscular blockers, removal of fluid by extracorporeal techniques, and percutaneous drainage of ascites should be instituted early. The indications for surgical decompression are still not clearly defined, but undoubtedly some patients benefit from it. It can be achieved with full-thickness laparostomy (midline or transverse subcostal) or through a subcutaneous linea alba fasciotomy. Despite the improvement in physiological variables and significant decrease in IAP, the effects of surgical decompression on organ function and outcome are less clear. Because of the significant morbidity associated with surgical decompression and the management of the ensuing open abdomen, more research is needed to define better the appropriate indications and techniques for surgical intervention.
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