ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2009
Components of the anorexia-cachexia syndrome: gastrointestinal symptom correlates of cancer anorexia.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Cancer Appetite and Symptom Questionnaire (CASQ) for Brazilian Patients: Cross-Cultural Adaptation and Validation Study.PloS one · 2016Trial
- A Phase II dose titration study of thalidomide for cancer-associated anorexia.Journal of pain and symptom management · 2012Trial
- Nutrition rehabilitation programs and cachexia clinics for anorexia-cachexia syndrome in patients with cancer.The oncologist · 2026Review
- Life Satisfaction Among Cancer Survivors With and Without Smell and Taste Dysfunction: Evidence from the National Health Interview Survey.medRxiv : the preprint server for health sciences · 2025Article
- Appetite Loss in Patients with Advanced Cancer Treated at an Acute Palliative Care Unit.Current oncology (Toronto, Ont.) · 2024Article
- Taste and Smell Alterations (TSAs) in Cancer Patients.Diseases (Basel, Switzerland) · 2024Review
- The Incidence and Management of Cancer-Related Anorexia During Treatment with Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitors.Cancer management and research · 2023Review
- MicroencapsulatedInternational journal of molecular sciences · 2021Article
- Multicentric prospective study of effect of dietary intake on quality of life for patients with end-stage cancers.Fujita medical journal · 2020Article
- Can Inflammatory and Nutritional Serum Markers Predict Chemotherapy Outcomes and Survival in Advanced Stage Nonsmall Cell Lung Cancer Patients?BioMed research international · 2019Article
- Alterations in inflammatory biomarkers and energy intake in cancer cachexia: a prospective study in patients with inoperable pancreatic cancer.Medical oncology (Northwood, London, England) · 2016Article
- Exploring the views of parents regarding dietary habits of their young cancer-surviving children.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Article
- Symptoms in advanced pancreatic cancer are of importance for energy intake.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Article
- Clinical outcomes and contributors to weight loss in a cancer cachexia clinic.Journal of palliative medicine · 2011Article
- More is better: a multimodality approach to cancer cachexia.The oncologist · 2010Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCancer-related anorexia is traditionally considered part of a complex but ill-defined anorexia-cachexia syndrome in which anorexia is intimately associated with other gastrointestinal (GI) symptoms and weight loss. We surveyed cancer patients with anorexia to learn more about the relationship between anorexia and these symptoms. MATERIALS AND
methodsA 22-item GI questionnaire assessed the severity of anorexia and the prevalence of concurrent GI symptoms, including taste changes, food aversions, altered sense of smell, and diurnal food intake changes. The relationship between anorexia severity and anticancer therapy and prior menstrual or pregnancy-related appetite changes was also assessed.
resultsNinety-five of 101 patients with anorexia surveyed had complete data. Seventy-eight percent of them had moderate or severe anorexia. Abnormal diurnal appetite variation, taste changes, and food aversions were present in over 50% of all those with anorexia. Judged by the numerical rating scale, the worse the anorexia, the more prevalent were early satiety, constipation, vomiting, and food aversions. Those with more severe anorexia had greater weight loss, and worse performance status. Anorexia severity did not correlate with that during prior menses/pregnancy or antitumor therapy.
conclusionsEvaluation of multiple other GI symptoms is important in understanding the total experience of cancer anorexia. Early satiety, taste changes, food aversions, and altered sense of smell are important accompanying GI symptoms. Most validated anorexia tools do not assess these commonly associated GI symptoms. Future research should develop a comprehensive anorexia symptom questionnaire.
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