ArticleNature nanotechnology2009
Mechanically interlocked calix[4]arene dimers display reversible bond breakage under force.
Article in Nature nanotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Forces in mechanically interlocked materials.Chemical Society reviews · 2026Review
- Force Reveals Hidden Conformations and Dissociation Pathways in Individual π-Interacting Dimers.Angewandte Chemie (International ed. in English) · 2026Article
- ConeBeilstein journal of organic chemistry · 2026Article
- Distinctive features and challenges in catenane chemistry.Chemical science · 2022Review
- Dynamic force spectroscopy of synthetic oligorotaxane foldamers.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Hierarchical Assembly of an Interlocked MAngewandte Chemie (International ed. in English) · 2018Article
- Synthetic oligorotaxanes exert high forces when folding under mechanical load.Nature nanotechnology · 2018Article
- Mechanochemistry of the mechanical bond.Chemical science · 2018Review
- Direct correlation of single-molecule properties with bulk mechanical performance for the biomimetic design of polymers.Nature materials · 2014Article
- A single synthetic small molecule that generates force against a load.Nature nanotechnology · 2011Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The physics of nanoscopic systems is strongly governed by thermal fluctuations that produce significant deviations from the behaviour of large ensembles. Stretching experiments of single molecules offer a unique way to study fundamental theories of statistical mechanics, as recently shown for the unzipping of RNA hairpins. Here, we report a molecular design based on oligo calix[4]arene catenanes-calixarene dimers held together by 16 hydrogen bridges-in which loops within the molecules limit how far the calixarene nanocapsules can be separated. This mechanically locked structure tunes the energy landscape of dimers, thus permitting the reversible rupture and rejoining of the individual nanocapsules. Experimental evidence, supported by molecular dynamics simulations, reveals the presence of an intermediate state involving the concerted rupture of the 16 hydrogen bridges. Stochastic modelling using a three-well potential under external load allows reconstruction of the energy landscape.
Indexed as
Identifiers
19350031What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.