Double Helix of breast cancer therapy: intertwining the Halsted and Fisher hypotheses.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

7 citing papers in PubMed.

1. Predictors of early distant metastasis in women with breast cancer.Journal of cancer research and clinical oncology · 2013
   Trial
2. NRG-BR002: A Randomized Phase II/III Trial of Metastasis-Directed Ablation With First-Line Systemic Therapy for Oligometastatic Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
   Article
3. The double agents in liquid biopsy: promoter and informant biomarkers of early metastases in breast cancer.Molecular cancer · 2022
   Review
4. In pursuit of a flawless aphrodite: paving the way to scarless oncoplastic breast surgery.Cancer communications (London, England) · 2019
   Article
5. The role of radiation therapy in the treatment of metastatic cancer.Clinical & experimental metastasis · 2018
   Review
6. What Tumor Dynamics Modeling Can Teach us About Exploiting the Stem-Cell View for Better Cancer Treatment.Cancer informatics · 2015
   Review
7. Significance of ipsilateral breast tumor recurrence after breast conserving treatment: role of surgical removal.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2013
   Article

Corrections and comments

• Commented on by
  The breast cancer alternative hypothesis: is there evidence to justify replacing it?2010
• Commented on by
  Local control, survival, and the Fisher hypothesis.2010
• Comment on
  Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in patients treated by breast-conserving therapy in five National Surgical Adjuvant Breast and Bowel Project protocols of node-negative breast cancer.2009

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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