ReviewInternational review of cell and molecular biology2009
Chapter 6: cubic membranes the missing dimension of cell membrane organization.
Review in International review of cell and molecular biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
56 citing papers in PubMed.
- Diffusion through complex confining environments: Motion in fluctuating porous membrane structures.Biophysical journal · 2026Article
- Polymerization from Lipid Membranes.Biomacromolecules · 2026Article
- On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation.The FEBS journal · 2025Article
- Lipid liquid-crystalline nanoparticles as a suitable platform for accommodating sensitive membrane proteins: monitoring the activity of HMG-CoA reductase.Journal of nanobiotechnology · 2025Article
- Article
- Limits of economy and fidelity for programmable assembly of size-controlled triply periodic polyhedra.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Composite material in the sea urchinJournal of the Royal Society, Interface · 2024Article
- Diversification of Plastid Structure and Function in Land Plants.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Characterization of intracellular membrane structures derived from a massive expansion of endoplasmic reticulum (ER) membrane due to synthetic ER-membrane-resident polyproteins.Journal of experimental botany · 2024Article
- Article
- Characterizing the Self-Assembly Properties of Monoolein Lipid Isosteres.The journal of physical chemistry. B · 2023Article
- Recent progress on the activation of the cGAS-STING pathway and its regulation by biomolecular condensation.Journal of molecular cell biology · 2022Article
- SPIRE-a software tool for bicontinuous phase recognition: application for plastid cubic membranes.Plant physiology · 2022Article
- Interaction of Metallic Nanoparticles With Biomimetic Lipid Liquid Crystalline Cubic Interfaces.Frontiers in bioengineering and biotechnology · 2022Article
- Light-Induced Smooth Endoplasmic Reticulum Rearrangement in a Unique Interlaced Compartmental Pattern in Macaca mulatta RPE.Investigative ophthalmology & visual science · 2021Article
- Loose Morphology and High Dynamism of OSER Structures Induced by the Membrane Domain of HMG-CoA Reductase.International journal of molecular sciences · 2021Article
- IntEResting structures: formation and applications of organized smooth endoplasmic reticulum in plant cells.Plant physiology · 2021Article
- Coronavirus-Induced Host Cubic Membranes and Lipid-Related Antiviral Therapies: A Focus on Bioactive Plasmalogens.Frontiers in cell and developmental biology · 2021Review
- Potential Role of Plasmalogens in the Modulation of Biomembrane Morphology.Frontiers in cell and developmental biology · 2021Review
- The Role of Membranes and Lipid-Protein Interactions in the Mg-Branch of Tetrapyrrole Biosynthesis.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Biological membranes are among the most fascinating assemblies of biomolecules: a bilayer less than 10 nm thick, composed of rather small lipid molecules that are held together simply by noncovalent forces, defines the cell and discriminates between "inside" and "outside", survival, and death. Intracellular compartmentalization-governed by biomembranes as well-is a characteristic feature of eukaryotic cells, which allows them to fulfill multiple and highly specialized anabolic and catabolic functions in strictly controlled environments. Although cellular membranes are generally visualized as flat sheets or closely folded isolated objects, multiple observations also demonstrate that membranes may fold into "unusual", highly organized structures with 2D or 3D periodicity. The obvious correlation of highly convoluted membrane organizations with pathological cellular states, for example, as a consequence of viral infection, deserves close consideration. However, knowledge about formation and function of these highly organized 3D periodic membrane structures is scarce, primarily due to the lack of appropriate techniques for their analysis in vivo. Currently, the only direct way to characterize cellular membrane architecture is by transmission electron microscopy (TEM). However, deciphering the spatial architecture solely based on two-dimensionally projected TEM images is a challenging task and prone to artifacts. In this review, we will provide an update on the current progress in identifying and analyzing 3D membrane architectures in biological systems, with a special focus on membranes with cubic symmetry, and their potential role in physiological and pathophysiological conditions. Proteomics and lipidomics approaches in defined experimental cell systems may prove instrumental to understand formation and function of 3D membrane morphologies.
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